Pan-genome and comparative genome analyses of propionibacterium acnes reveal its genomic diversity in the healthy and diseased human skin microbiome

S Tomida, L Nguyen, BH Chiu, J Liu, E Sodergren… - mbio, 2013 - Am Soc Microbiol
Propionibacterium acnes constitutes a major part of the skin microbiome and contributes to
human health. However, it has also been implicated as a pathogenic factor in several …

In vitro Antimicrobial Activity of Acne Drugs Against Skin-Associated Bacteria

MAT Blaskovich, AG Elliott, AM Kavanagh, S Ramu… - Scientific reports, 2019 - nature.com
Acne is a common skin affliction that involves excess sebum production and modified lipid
composition, duct blockage, colonization by bacteria, and inflammation. Acne drugs target …

Skin dysbiosis and Cutibacterium acnes biofilm in inflammatory acne lesions of adolescents

I Cavallo, F Sivori, M Truglio, F De Maio, F Lucantoni… - Scientific Reports, 2022 - nature.com
Acne vulgaris is a common inflammatory disorder affecting more than 80% of young
adolescents. Cutibacterium acnes plays a role in the pathogenesis of acne lesions, although …

The role of Propionibacterium acnes in acne pathogenesis: facts and controversies

C Dessinioti, AD Katsambas - Clinics in dermatology, 2010 - Elsevier
We have come a long way since 1896, when it was first suggested that Propionibacterium
acnes, found in acne lesions, was the cause of acne. Although several lines of evidence …

Propionibacterium acnes in the pathogenesis and immunotherapy of acne vulgaris

PF Liu, YD Hsieh, YC Lin, A Two… - Current Drug …, 2015 - ingentaconnect.com
Acne vulgaris, a multi-factorial disease, is one of the most common skin diseases, affecting
an estimated 80% of Americans at some point during their lives. The gram-positive and …

From new findings in acne pathogenesis to new approaches in treatment

HPM Gollnick - Journal of the European Academy of …, 2015 - Wiley Online Library
Acne is a chronic disease of the pilosebaceous unit which is most common during
adolescence. Four factors are believed to play a key role in the development of acne …

Antibiotic resistant Cutibacterium acnes among acne patients in Jordan: a cross sectional study

E Alkhawaja, S Hammadi, M Abdelmalek… - BMC dermatology, 2020 - Springer
Background Antibiotics have been used for decades against Cutibacterium acnes
(previously known as Propionibacterium acnes; C. acnes). Alarmingly, antibiotic resistance …

Antagonism between Staphylococcus epidermidis and Propionibacterium acnes and its genomic basis

GJM Christensen, CFP Scholz, J Enghild, H Rohde… - BMC genomics, 2016 - Springer
Abstract Background Propionibacterium acnes and Staphylococcus epidermidis live in close
proximity on human skin, and both bacterial species can be isolated from normal and acne …

Regional variations of cutaneous propionibacteria

KJ McGINLEY, GF Webster… - Applied and …, 1978 - Am Soc Microbiol
Propionibacterium acnes, P. avidum, and P. granulosum were quantitatively measured in 50
young adults. The scalp, forehead, external auditory canal, alae nasi, anterior nares, groin …

The Complete Genome Sequence of Propionibacterium Acnes, a Commensal of Human Skin

H Bruggemann, A Henne, F Hoster, H Liesegang… - Science, 2004 - science.org
Propionibacterium acnes is a major inhabitant of adult human skin, where it resides within
sebaceous follicles, usually as a harmless commensal although it has been implicated in …