The effects of acute administration of captopril on heart rate, blood pressure and
physiological responses to head-up tilt, hand-grip, exercise and Valsalva manoeuvre were …

1 The effect of captopril on autonomic reflex functions has been investigated in fifteen
patients with essential hypertension by examining their responses to tests of baroreceptor …

Absent reflex tachycardia with captopril therapy suggests blunting of circulatory reflexes,
perhaps contributing to antihypertensive efficacy, and angiotensin converting enzyme …

Captopril lowers blood pressure without increasing heart rate and plasma norepinephrine,
which suggests that this drug may potentiate arterial baroreflexes. In eight subjects with …

The usual regimens of captopril-twice or thrice daily administration-are based on the
duration of the decrease in plasma angiotensin II induced by captopril. In a study performed …

Captopril (50 mg orally) produced a significant fall in systolic and diastolic blood pressure in
six normotensive sodium replete subjects, without a rise in heart rate. On captopril, there …

1. The effect of captopril 12.5 mg three times daily for 14 days on baroreflex sensitivity was
investigated in six normotensive salt‐replete male subjects. 2. Baroreflex sensitivity [delta R …

1. The reflex effects of intravenous phenylephrine, sodium nitroprusside or acute
haemorrhage in rabbits were examined as indices of baroreceptors reflex function. 2. The …

Eight diabetic subjects with moderately elevated blood pressure (BP)(systolic (SBP) greater
than 140 and/or diastolic (DBP) greater than 90 mmHg) were studied. Each had evidence of …

Previous studies from our laboratory have shown that chronic intracerebroventricular
administration of captopril attenuates the development of hypertension in the spontaneously …