COVID-19 linked to rise in anti-MDA5 autoimmunity

J McHugh - Nature Reviews Rheumatology, 2024 - nature.com
COVID-19 linked to rise in anti-MDA5 autoimmunity | Nature Reviews Rheumatology Skip to
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[HTML][HTML] Anti-MDA5 antibody linking COVID-19, type I interferon, and autoimmunity: a case report and systematic literature review

A Tonutti, F Motta, A Ceribelli, N Isailovic… - Frontiers in …, 2022 - frontiersin.org
Introduction The SARS-CoV-2 infection has been advocated as an environmental trigger for
autoimmune diseases, and a paradigmatic example comes from similarities between COVID …

Two Cases of Slowly-Progressive Anti-MDA-5 ILD Post COVID-19 Infection

SA Armstrong, AA Menon, D Sese - A33. PUSHING THE IMMUNE …, 2024 - atsjournals.org
Introduction: Anti-Melanoma Differentiation-Associated Gene 5 (MDA-5) myositis is a rare
subset of dermatomyositis known for its association with rapidly progressive interstitial lung …

What is common to MDA5 and COVID-19?

DN Zohar, Y Shoenfeld - … , COVID-19, Post-COVID19 Syndrome and COVID …, 2023 - Elsevier
Respiratory complaints and nonspecific systemic symptoms combined with bilateral ground
glass opacities on chest imaging constitute the clinical and radiological picture of both …

Is COVID-19 the culprit? A case of anti-MDA5 antibody positivity in a rapidly progressive organizing pneumonia

L McNamara, VA Brady - TP31. TP031 INTERESTING CASES …, 2021 - atsjournals.org
Discussion: Anti-MDA5 antibody positivity has been implicated in rapidly progressive ILD
often refractory to conventional treatments like steroids. While this patient's pathology …

Appearance of anti-MDA5 antibody-positive dermatomyositis after COVID-19 vaccination

T Sugimoto, A Yorishima, N Oka… - Modern …, 2023 - academic.oup.com
The direct causes of dermatomyositis, a common autoimmune disease, have not yet been
accurately identified, but several studies have linked this condition to various patient …

What can we learn from rapidly progressive interstitial lung disease related to anti-MDA5 dermatomyositis in the management of COVID-19?

E De Lorenzis, G Natalello, L Gigante… - Autoimmunity …, 2020 - ncbi.nlm.nih.gov
Coronavirus disease 2019 (COVID-19) is a newly recognized systemic condition due to the
SARS-CoV-2 infection. As rheumatologists, we often found analogies between vascular …

[HTML][HTML] COVID-19 as a putative trigger of anti-MDA5-associated dermatomyositis with acute respiratory distress syndrome (ARDS) requiring lung transplantation, a …

K Anderle, K Machold, HP Kiener, D Bormann… - BMC rheumatology, 2022 - Springer
Background Autoimmune disease following COVID-19 has been studied intensely since the
beginning of the pandemic. Growing evidence indicates that SARS-CoV-2 infection, by …

MDA5-autoimmunity and Interstitial Pneumonitis Contemporaneous with the COVID-19 Pandemic (MIP-C)

K Iqbal, S Sinha, P David, G De Marco, S Taheri… - medRxiv, 2023 - medrxiv.org
Background: Anti-MDA5 (Melanoma differentiation-associated protein-5) positive
dermatomyositis (MDA5+-DM) is characterised by rapidly progressive interstitial lung …

[HTML][HTML] MDA5-autoimmunity and interstitial pneumonitis contemporaneous with the COVID-19 pandemic (MIP-C)

P David, S Sinha, K Iqbal, G De Marco, S Taheri… - Ebiomedicine, 2024 - thelancet.com
Summary Background Anti-MDA5 (Melanoma differentiation-associated protein-5) positive
dermatomyositis (MDA5+-DM) is characterised by rapidly progressive interstitial lung …