Ovarian cancer is the major cause of death in women with gynecologic malignancies. There
is emerging evidence that Androgen/androgen receptor (AR) signaling plays a critical role in …

Emerging evidence has suggested that androgen receptor signaling plays an important role
in ovarian cancer outgrowth. Specifically, androgen receptor activation appears to be …

Ovarian cancer (OVCA) arises from three cellular origins, namely surface epithelial cells,
germ cells, and stromal cells. More than 85% of OVCAs are EOCs (epithelial ovarian …

Endometrial cancer (EC) and ovarian cancer are common gynaecological malignancies.
The impact of androgen action in these cancers is poorly understood; however, there is …

There are three main types of cancer in the female reproductive system, specifically ovarian
cancer (OVCA), endometrial cancer (EC), and cervical cancer (CC). They are common …

OBJECTIVE: Length of a polymorphic cytosine-adenine-guanine (CAG) repeat in the
androgen receptor (AR) may inversely correlate with AR activity. We have identified an …

Background Biological and epidemiologic evidence suggested that androgen and its
receptor may play an important role in ovarian carcinogenesis. However, results of previous …

Background Altered androgen hormone homeostasis and androgen receptor (AR) activity
have been implicated in ovarian carcinogenesis but the relationship between AR expression …

Abstract Learning Objectives After completing this course, the reader will be able to: Explain
the role of the androgen axis in the development of ovarian cancer. Discuss the potential …

Epidemiological studies have implicated androgens in the etiology and progression of
epithelial ovarian cancer. We previously reported that some androgen responses were …