Objectives Tumour cells produce factors such as interleukin 10 (IL-10), transforming growth
factor β 1 (TGF-β 1) and vascular endothelial growth factor (VEGF) that suppress the function …

The immune system in patients with cancer often fails to control tumour growth because of
deficient immunogenicity of tumour cells. Ganoderma lucidum polysaccharides (Gl‐PS) are …

Transforming growth factor β (TGF-β), interleukin-10 (IL-10), and vascular endothelial growth
factor (VEGF) are three of the commonly studied cytokines playing an important role in tumor …

Immune responses to tumor-associated antigens are often detectable in tumor-bearing
hosts, but they fail to eliminate malignant cells or prevent development of metastases. Tumor …

It is well‐documented that macrophages have the functions to regulate antitumor immune
response. Antitumor response can be launched by a series of events, starting with …

Some cytokines, such as interleukin-2 (IL-2), interferon-γ (IFN-γ) and tumor necrosis factor-α
(TNF-α), produced by lymphocytes might play an important role in anti-tumor immunity and …

The present study was designed to determine in vivo efficacy of Ganoderma lucidum
polysaccharides (Gl-PS) for enhancing the activity of immunological effector cells in …

Ganoderma lucidum (G. lucidum), a basidiomycete white rot fungus, has long been
prescribed to prevent and treat various human diseases, particularly in China, Japan, and …

Preclinical studies have established that the Ganoderma lucidum polysaccharide (GLPS)
fractions have potent anti‐tumor activity, which has been associated with the immuno …

The antitumor and immunomodulatory activity of broken-spore of Ganoderma lucidum
polysaccharides (Gl-BSP) were investigated in vivo and in vitro. It was showed that Gl-BSP …