Proteins are essential and abundant components of cellular membranes. Being densely
packed within the limited surface area, proteins fulfil essential tasks for life, which include …

Cellular membranes are typically decorated with a plethora of embedded and adsorbed
macromolecules, eg proteins, that participate in numerous vital processes. With typical …

In cell membranes, membrane proteins occupy∼ 30% of the total surface area. Crowding
effects similar to those in the solution phase are thus to be expected. In addition, there are …

Diffusion of transmembrane and peripheral membrane-bound proteins within the crowded
cellular membrane environment is essential to diverse biological processes including …

Clustering of extracellular ligands and proteins on the plasma membrane is required to
perform specific cellular functions, such as signaling and endocytosis. Attractive forces that …

Cells mediate interactions with the extracellular environment through a crowded assembly of
transmembrane proteins, glycoproteins and glycolipids on their plasma membrane. The …

Association of proteins to cellular membranes is involved in various biological processes.
Various theoretical models have been developed to describe this adsorption mechanism …

The habitat in which proteins exert their function contains up to 400 g/L of macromolecules,
most of which are proteins. The repercussions of this dense environment on protein …

Crowding of asymmetrically-distributed membrane proteins has been recently recognized as
an important factor in remodeling of biological membranes, for example during transport …

Atomistic molecular dynamics simulations of concentrated protein solutions in the presence
of a phospholipid bilayer are presented to gain insights into the dynamics and interactions at …