Macromolecular crowding dramatically affects cellular processes such as protein folding and
assembly, regulation of metabolic pathways, and condensation of DNA. Despite increased …

The compartmentalization of the plasma membrane is essential for cells to perform
specialized biochemical functions, in particular those responsible for intracellular and …

It is demonstrated that fluorescence resonance energy transfer may be used to determine
the fractal dimension of aggregates of membrane-bound proteins. Theoretical and …

The intercellular environment is known to be very different from the environment where most
of the elementary biological processes are studied in the laboratory. As a result, there was a …

Over the last several decades, an impressive array of advanced microscopic and analytical
tools, such as single-particle tracking and nanoscopic fluorescence correlation …

The effect of macromolecular crowding on protein structure and dynamics has mostly been
explained on the basis of the excluded volume effect, its origin being entropic. In recent …

The spatial organization of cell membrane glycoproteins and glycolipids is critical for
mediating the binding of ligands, receptors, and macromolecules on the plasma membrane …

To probe the complexity of the cell membrane organization and dynamics, it is important to
obtain simple physical observables from experiments on live cells. Here we show that …

Biological and biomimetic membranes display complex shapes with nonuniform curvature.
Because the interaction of adhesive nanoparticles with such membranes depends on the …

Curved membranes are an essential feature of dynamic cellular structures, including
endocytic pits, filopodia protrusions and most organelles,. It has been proposed that …