Background Yersinia pestis, the causative agent of plague, is a pathogen with a tremendous
ability to cause harm and panic in populations. Due to the severity of plague and its potential …

Plague caused by Yersinia pestis manifests itself in bubonic, septicemic, and pneumonic
forms. Although the US Food and Drug Administration recently approved levofloxacin, there …

Yersinia pestis is one of the world's most virulent human pathogens. Inhalation of this Gram‐
negative bacterium causes pneumonic plague, a rapidly progressing and usually fatal …

Yersinia pestis is a gram-negative human pathogen that uses a type III secretion system to
deliver virulence factors into human hosts. The delivery is contact-dependent and it has …

Plague, an infectious disease that reached catastrophic proportions during three pandemics,
continues to be a legitimate public health concern worldwide. Although antibiotic therapy for …

Yersinia pestis, the causative organism of plague, produces V antigen (LcrV), a bifunctional
protein with regulatory and virulence roles that has been shown to be highly protective …

Plague, which is initiated by Yersinia pestis infection, is a fatal disease that progresses
rapidly and leads to high mortality rates if not treated. Antibiotics are an effective plague …

Despite many decades of intensive studies of Yersinia pestis, the causative agent of plague,
there is no safe and efficient vaccine against this devastating disease. A recently developed …

Yersinia pestis is the etiologic agent of plague that has killed more than 200 million people
throughout the recorded history of mankind. Antibiotics may provide little immediate relief to …

Current subunit vaccines provide partial protection against pneumonic plague if the infecting
Y. pestis strain is encapsulated (F1+). Here we describe YadC, a novel Y. pestis outer …