Chondroitin sulfate and heparan sulfate proteoglycans are major components of the cell
surface and extracellular matrix in the brain. Both chondroitin sulfate and heparan sulfate …

Growth-inhibitory chondroitin sulfate proteoglycans (CSPG) are a primary target for
therapeutic strategies after spinal cord injury because of their contribution to the inhibitory …

The precise contribution of different CS-GAGs to CSPG-mediated inhibition of axonal growth
after CNS injury is unknown. Quantification of the CS-GAGs in uninjured and injured brain …

Proteoglycans, as part of the extracellular or cell-surface milieu of most tissues and organ
systems, play important roles in morphogenesis by modulating cell-matrix or cell-cell …

Chondroitin sulfate (CS) proteoglycans in perineuronal nets (PNNs) from the central nervous
system (CNS) are involved in the control of plasticity and memory. Removing PNNs …

Aggrecan family proteoglycans, phosphacan/RPTPζ/β, and neuroglycan C (NGC) are the
major classes of chondroitin sulfate proteoglycan in the developing mammalian brain. A …

The repair of myelin, termed remyelination, is a regenerative process that occurs within the
central nervous system in conditions such as multiple sclerosis. Remyelination is enabled by …

DSD-1-PG is a chondroitin sulfate proteoglycan (CSPG) expressed by glial cells that can
promote neurite outgrowth from rat embryonic mesencephalic (E14) and hippocampal (E18) …

Chondroitin sulfate proteoglycans (CSPGs) are inhibitory extracellular matrix molecules that
are upregulated after CNS injury. Degradation of CSPGs using the enzyme chondroitinase …

Chondroitin sulfate proteoglycan (CS‐PG) was purified from rat brain and examined for its
effect on neurite outgrowth in primary cultures of embryonic rat neocortical neurons. Neurite …