We previously discovered that mutations of the human FOXP2 gene cause a monogenic
communication disorder, primarily characterized by difficulties in learning to make …

Rare mutations of the FOXP2 transcription factor gene cause a monogenic syndrome
characterized by impaired speech development and linguistic deficits. Recent genomic …

Highlights•Rare variants disrupting speech, in genes like FOXP2, give insight into
neurobiology of key human traits.•Neural functions of FOXP2 are being studied in human …

Mutations in FOXP2, a member of the forkhead family of transcription factor genes, are the
only known cause of developmental speech and language disorders in humans. To date …

Developmental disorders affecting speech and language are highly heritable, but very little
is currently understood about the neuromolecular mechanisms that underlie these traits …

Mutations in the FOXP2 gene cause a severe communication disorder involving speech
deficits (developmental verbal dyspraxia), accompanied by wide-ranging impairments in …

Rare disruptions of FOXP2 have been strongly implicated in deficits in language
development. Research over the past decade has suggested a role in the formation of …

The discovery of the FOXP2 transcription factor, and its implication in a rare severe human
speech and language disorder, has led to two decades of empirical studies focused on …

▪ Abstract A significant number of individuals have unexplained difficulties with acquiring
normal speech and language, despite adequate intelligence and environmental stimulation …

De novo disruptions of the neural transcription factor FOXP1 are a recently discovered, rare
cause of sporadic intellectual disability (ID). We report three new cases of FOXP1-related …