Sequence Learning in a 6-OHDA Mouse Model of Parkinson's Disease

A Gribbin - 2024 - digitalcommons.macalester.edu
Abstract Parkinson's disease (PD), a neurodegenerative disorder originating in the
dopaminergic cells of the basal ganglia, is characterized by severe motor impairments such …

[HTML][HTML] Motor sequence learning deficits in idiopathic Parkinson's disease are associated with increased substantia nigra activity

E Tzvi, R Bey, M Nitschke, N Brüggemann… - Frontiers in Aging …, 2021 - frontiersin.org
Previous studies have shown that persons with Parkinson's disease (pwPD) share specific
deficits in learning new sequential movements, but the neural substrates of this impairment …

Functional imaging of sequence learning in Parkinson's disease

M Carbon, D Eidelberg - Journal of the neurological sciences, 2006 - Elsevier
Sequence learning, a cognitive task linked to cortico-striatal function, is impaired in
Parkinson's disease (PD). We chose this task as a behavioral paradigm to study the …

Early stage Parkinson's disease patients and normal volunteers: comparative mechanisms of sequence learning

MJ Mentis, V Dhawan, A Feigin, D Delalot… - Human brain …, 2003 - Wiley Online Library
Early‐stage nondemented Parkinson's disease (PD (es)) patients can learn short but not
long sequences as well as controls. We have previously shown that to achieve normal …

[HTML][HTML] Implicit sequence learning in people with Parkinson's disease

KR Gamble, TJ Cummings Jr, SE Lo… - Frontiers in human …, 2014 - frontiersin.org
Implicit sequence learning involves learning about dependencies in sequences of events
without intent to learn or awareness of what has been learned. Sequence learning is related …

Effect of dopaminergic medications on the time course of explicit motor sequence learning in Parkinson's disease

Y Kwak, MLTM Müller, NI Bohnen… - Journal of …, 2010 - journals.physiology.org
The capacity to learn new motor sequences is fundamental to adaptive motor behavior. The
early phase of motor sequence learning relies on the ventral and anterior striatal circuitry …

l-DOPA changes ventral striatum recruitment during motor sequence learning in Parkinson's disease

Y Kwak, MLTM Müller, NI Bohnen, P Dayalu… - Behavioural brain …, 2012 - Elsevier
We previously reported a differential effect of dopaminergic medication across the time
course of motor sequence learning in early stage Parkinson's (PD) patients [1]. There was a …

Early Parkinson's disease: longitudinal changes in brain activity during sequence learning

M Carbon, K Reetz, MF Ghilardi, V Dhawan… - Neurobiology of …, 2010 - Elsevier
Impairment of sequence learning is common in Parkinson's disease (PD), but the time
course of this cognitive abnormality is not known. We assessed longitudinal changes in …

Impaired habit acquisition and striatal dysfunction in early Parkinson's disease

M Bendale - 2021 - search.proquest.com
Parkinson's disease (PD) is characterized by the progressive degeneration of substantia
nigra pars compacta (SNc) dopamine (DA) neurons resulting in striatal DA depletion and …

Dissociating sequence learning performance in Parkinson? s disease: Visuomotor sequence acquisition and pattern judgment on a serial reaction time task

J McDowall - Acta Neurobiologiae Experimentalis, 2011 - ane.pl
In this study, the sequence learning performance of 16 non-demented patients with
Parkinson's disease (PD) was compared with 18 age-matched healthy controls on a verbal …