A beneficial role of rooibos in diabetes mellitus: a systematic review and meta-analysis

M Sasaki, N Nishida, M Shimada - Molecules, 2018 - mdpi.com
In a rapid increase in cases of diabetes mellitus worldwide, there has been interested in the
use of plant-derived polyphenols as nutraceuticals to prevent the onset and progression of …

Antidiabetic effect of green rooibos (Aspalathus linearis) extract in cultured cells and type 2 diabetic model KK-Ay mice

R Kamakura, MJ Son, D de Beer, E Joubert, Y Miura… - Cytotechnology, 2015 - Springer
Previous studies have demonstrated antidiabetic effects for rooibos (Aspalathus linearis)
and aspalathin (ASP), one of its main polyphenols. Rooibos, an endemic plant of South …

Aspalathin improves hyperglycemia and glucose intolerance in obese diabetic ob/ob mice

MJ Son, M Minakawa, Y Miura, K Yagasaki - European journal of nutrition, 2013 - Springer
Purpose Although several researches have demonstrated that rooibos extract has
hypoglycemic effect, the role of aspalathin, a main polyphenol in the extract, remains …

Acute assessment of an aspalathin-enriched green rooibos (Aspalathus linearis) extract with hypoglycemic potential

CJF Muller, E Joubert, D De Beer, M Sanderson… - Phytomedicine, 2012 - Elsevier
Rooibos, an endemic South African plant, known for its use as herbal tea, has potential as
an antidiabetic herbal product, following recent demonstration of the glucose lowering effect …

Okra ameliorates hyperglycaemia in pre-diabetic and type 2 diabetic patients: A systematic review and meta-analysis of the clinical evidence

K Mokgalaboni, SL Lebelo, P Modjadji… - Frontiers in …, 2023 - frontiersin.org
Background: Despite the use of available pharmaceutical drugs, high rates of metabolic
diseases and cardiovascular disorders are alarming. This calls for alternative therapies that …

Arctium lappa Lam. and Its Related Lignans Improve Hyperglycemia and Dyslipidemia in Diabetic Rodent Models: A Systematic Review and Meta-Analysis

S Watanabe, S Yamabe, M Shimada - Nutraceuticals, 2022 - mdpi.com
Research on nutraceuticals has focused on reducing the onset, progression, and significant
consequences of diabetes mellitus. Arctium lappa Lam. is a great source of plant fibers and …

New insights into the efficacy of aspalathin and other related phytochemicals in type 2 diabetes—A review

CJF Muller, E Joubert, N Chellan, Y Miura… - International Journal of …, 2021 - mdpi.com
In the pursuit of bioactive phytochemicals as a therapeutic strategy to manage metabolic risk
factors for type 2 diabetes (T2D), aspalathin, C-glucosyl dihydrochalcone from rooibos …

Effects of okra (Abelmoschus esculentus (L.) Moench) on glycemic markers in animal models of diabetes: A systematic review

AB Sereno, CD Pinto, FA Andrade, MAB da Silva… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Okra (Abelmoschus esculentus (L.) Moench) is
traditionally used by different populations of Africa, América, Asia, and Europa to control …

Role of polyphenols in the management of diabetic complications

J Raina, A Firdous, G Singh, R Kumar, C Kaur - Phytomedicine, 2023 - Elsevier
Abstract Background Diabetic Mellitus is an endocrine disorder that will affect, about 693
million adults by 2045 worldwide,(> 50% increase from 2017). The conventional treatment of …

Therapeutic effects of an aspalathin-rich green rooibos extract, pioglitazone and atorvastatin combination therapy in diabetic db/db mice

O Patel, CJF Muller, E Joubert, B Rosenkranz, J Louw… - PloS one, 2021 - journals.plos.org
Oral therapeutics used to treat type 2 diabetes and cardiovascular disease often fail to
prevent the progression of disease and their comorbidities. Rooibos (Aspalathus linearis) …