p38 and STAT3 activation by vGPCR in KSHV-infected cells
M Liu, S Guo - Virus Adaptation and Treatment, 2010 - Taylor & Francis
The molecular mechanism whereby viral G protein-coupled receptor (vGPCR) signaling
regulates vascular endothelial growth factor (VEGF) expression in Kaposi sarcoma (KS) …
regulates vascular endothelial growth factor (VEGF) expression in Kaposi sarcoma (KS) …
[HTML][HTML] Initiation of angiogenic Kaposi's sarcoma lesions
GS Hayward - Cancer cell, 2003 - cell.com
A new mouse model reported in this issue of Cancer Cell implies that VEGF/KDR-mediated
paracrine effects induced by the lytic cycle vGPCR signaling protein encoded by human …
paracrine effects induced by the lytic cycle vGPCR signaling protein encoded by human …
Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/KDR
C Bais, A Van Geelen, P Eroles, A Mutlu, C Chiozzini… - Cancer cell, 2003 - cell.com
The G protein-coupled receptor oncogene (vGPCR) of the Kaposi's sarcoma (KS)
associated herpesvirus (KSHV), an oncovirus implicated in angioproliferative neoplasms …
associated herpesvirus (KSHV), an oncovirus implicated in angioproliferative neoplasms …
The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor promotes endothelial cell survival through the activation of Akt/protein kinase B
The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor (KSHV-GPCR) is
a key molecule in the pathogenesis of Kaposi's sarcoma, playing a central role in the …
a key molecule in the pathogenesis of Kaposi's sarcoma, playing a central role in the …
Viral G protein-coupled receptor up-regulates Angiopoietin-like 4 promoting angiogenesis and vascular permeability in Kaposi's sarcoma
T Ma, BC Jham, J Hu, ER Friedman… - Proceedings of the …, 2010 - National Acad Sciences
Kaposi's sarcoma (KS) is an enigmatic vascular tumor thought to be a consequence of
dysregulated expression of the human herpesvirus-8 (HHV-8 or KSHV)-encoded G protein …
dysregulated expression of the human herpesvirus-8 (HHV-8 or KSHV)-encoded G protein …
KSHV G-protein coupled receptor vGPCR oncogenic signaling upregulation of Cyclooxygenase-2 expression mediates angiogenesis and tumorigenesis in Kaposi's …
MV Medina, AD´ Agostino, Q Ma, P Eroles… - PLoS …, 2020 - journals.plos.org
Kaposi's sarcoma-associated herpesvirus (KSHV) vGPCR is a constitutively active G protein-
coupled receptor that subverts proliferative and inflammatory signaling pathways to induce …
coupled receptor that subverts proliferative and inflammatory signaling pathways to induce …
Modulation of host gene expression by the constitutively active G protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus
AG Polson, D Wang, J DeRisi, D Ganem - Cancer research, 2002 - AACR
Kaposi's sarcoma-associated herpes virus (KSHV) infects B cells and microvascular
endothelium, and is linked to both lymphoid and endothelial neoplasms. KSHV encodes a G …
endothelium, and is linked to both lymphoid and endothelial neoplasms. KSHV encodes a G …
The Kaposi's Sarcoma–Associated Herpesvirus G Protein–Coupled Receptor as a Therapeutic Target for the Treatment of Kaposi's Sarcoma
S Montaner, A Sodhi, AK Ramsdell, D Martin, J Hu… - Cancer research, 2006 - AACR
The Kaposi's sarcoma–associated herpesvirus (KSHV) encodes a G protein–coupled
receptor (vGPCR) that has been implicated in the initiation of Kaposi's sarcoma, identifying …
receptor (vGPCR) that has been implicated in the initiation of Kaposi's sarcoma, identifying …
The angiogenic properties of Kaposi's sarcoma-associated herpesvirus encoded G-protein coupled receptor are reduced by flavopiridol, an inhibitor of cyclin …
H McFerrin, M Angelova, E Abboud, A Nelson… - Infectious Agents and …, 2010 - Springer
Kaposi's sarcoma-associated herpesvirus (KSHV/HHV8) has been identified as the etiologic
agent of Kaposi's sarcoma (KS), a multifocal highly vascularized neoplasm that is the most …
agent of Kaposi's sarcoma (KS), a multifocal highly vascularized neoplasm that is the most …
Akt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirus-encoded G protein-coupled receptor
We have recently engineered an in vivo endothelial cell-specific retroviral gene transfer
system and found that a single Kaposi's sarcoma (KS)-associated herpesvirus/human …
system and found that a single Kaposi's sarcoma (KS)-associated herpesvirus/human …