Three single-nucleotide polymorphisms in LPA account for most of the increase in lipoprotein (a) level elevation in African Americans compared with European …

JP Chretien, J Coresh, Y Berthier-Schaad… - Journal of medical …, 2006 - jmg.bmj.com
Background: The extent which universally common or population-specific alleles can
explain between-population variations in phenotypes is unknown. The heritable coronary …

Lp (a) and apoE polymorphisms in young South African Indians with myocardial infarction: cardiovascular topics

N Ranjith, RJ Pegoraro, L Rom, MC Rajput… - … journal of south Africa, 2004 - journals.co.za
Summary The lipoprotein (a)[Lp (a)] and apolipoprotein E (apoE) polymorphisms have been
shown to be important genetic determinants of cardiovascular risk. Their effect on coronary …

Effects of the apolipoprotein (a) size polymorphism on the lipoprotein (a) concentration in 7 ethnic groups

C Sandholzer, DM Hallman, N Saha, G Sigurdsson… - Human genetics, 1991 - Springer
Summary Apolipoprotein (a)[apo (a)] exhibits a genetic size polymorphism explaining about
40% of the variability in lipoprotein (a)[Lp (a)] concentration in Tyroleans. Lp (a) …

Heritability of apolipoprotein (a) traits in two-generational African-American and Caucasian families [S]

B Enkhmaa, E Anuurad, W Zhang, K Kim… - Journal of lipid …, 2019 - ASBMB
Heritability of LPA allele, apo (a) isoform sizes, and isoform-associated lipoprotein (a)[Lp (a)]
levels was studied in 82 Caucasian and African-American families with two parents and two …

Serum distribution of lipoprotein (a) in African Americans and Nigerians: Potential evidence for a genotype‐environmental effect

CN Rotimi, RS Cooper, SM Marcovina… - Genetic …, 1997 - Wiley Online Library
Differences in lipoprotein (a)[Lp (a)] levels across populations have been described and
blacks are known to have higher Lp (a) values compared to whites. However, environmental …

Lipoprotein (a), atherosclerosis, and apolipoprotein (a) gene polymorphism

U Pati, N Pati - Molecular Genetics and Metabolism, 2000 - Elsevier
High plasma lipoprotein (a)[Lp (a)] levels have been implicated as an independent risk
factor for coronary artery disease in Caucasians, Chinese, Africans, and Indians. Apo (a) that …

Genetics of plasma lipoprotein (a) concentrations

E Boerwinkle - Current Opinion in Lipidology, 1992 - journals.lww.com
Abstract Lipoprotein (a)[Lp (a)] is a low-density-like lipoprotein with the addition of a Lp (a)-
specific protein, apolipoprotein (a)[apo (a)]. Plasma concentrations of Lp (a) are a risk factor …

Contribution of apolipoprotein (a) size, pentanucleotide TTTTA repeat and C/T (+ 93) polymorphisms of the apo (a) gene to regulation of lipoprotein (a) plasma levels …

K Valenti, E Aveynier, S Leauté, F Laporte, AJ Hadjian - Atherosclerosis, 1999 - Elsevier
Several studies indicate that the inter-individual variation in plasma concentrations of
lipoprotein (a)(Lp (a)) is mainly under genetic control. To define the effect of three DNA …

Apo (a) isoforms do not predict risk for coronary heart disease in a Gulf Arab population

AO Akanji - Annals of clinical biochemistry, 2000 - journals.sagepub.com
It is well recognized that blood lipoprotein A [Lp (a)] levels constitute an important risk factor
for atherosclerotic vascular disease. In some populations, mainly Caucasian, Lp (a) levels …

Molecular basis of congenital lp (a) deficiency: a frequent apo (a)'null'mutation in caucasians

M Ogorelkova, A Gruber… - Human molecular …, 1999 - academic.oup.com
High plasma concentrations of lipoprotein (a)[Lp (a)], a covalent low-density lipoprotein-
apolipoprotein (a)[apo (a)] complex, are associated with coronary heart disease and stroke …