Lp (a) concentrations are related to plasma lipid concentrations

DL Rainwater - Atherosclerosis, 1996 - Elsevier
Lp (a) concentrations are controlled primarily by genetic variation at LPA, the locus encoding
the unique protein apo (a). However, the high heritability is in part a consequence of nearly …

Characterization of the genetic elements controlling lipoprotein (a) concentrations in Mexican Americans. Evidence for at least three controlling elements linked to LPA …

DL Rainwater, CM Kammerer, JL VandeBerg… - Atherosclerosis, 1997 - Elsevier
Analyses of 1163 samples from the San Antonio Family Heart Study revealed several
elements of genetic control of lipoprotein (a)(Lp (a)) concentrations in Mexican Americans …

Studies on apolipoprotein (a) phenotypes. Part 1. Phenotype frequencies in a healthy Japanese population

A Abe, A Noma - Atherosclerosis, 1992 - Elsevier
The frequency distribution for serum lipoprotein (a)(Lp (a)) concentrations in healthy
Japanese was highly skewed, with a mean±SD of 14.6±13.6 mg/dl and a median of 11.0 …

Associations of genetically predicted Lp (a)(lipoprotein [a]) levels with cardiovascular traits in individuals of European and African Ancestry

BA Satterfield, O Dikilitas, MS Safarova… - Circulation: Genomic …, 2021 - Am Heart Assoc
Background: Lp (a)(lipoprotein [a]) levels are higher in individuals of African ancestry (AA)
than in individuals of European ancestry (EA). We examined associations of genetically …

Lipoprotein (a) in homozygous familial hypercholesterolemia

HG Kraft, A Lingenhel, FJ Raal… - … , and vascular biology, 2000 - Am Heart Assoc
Lipoprotein (a)[Lp (a)] is a quantitative genetic trait that in the general population is largely
controlled by 1 major locus—the locus for the apolipoprotein (a)[apo (a)] gene. Sibpair …

Genetics and metabolism of lipoprotein (a) and their clinical implications (Part 1).

H Dieplinger, F Kronenberg - Wiener Klinische Wochenschrift, 1999 - europepmc.org
The human plasma lipoprotein Lp (a) has gained considerable clinical interest as a
genetically determined risk factor for atherosclerotic vascular diseases. Numerous (including …

Lipoprotein (a): a unique independent risk factor for coronary artery disease

A Manocha, LM Srivastava - Indian journal of clinical biochemistry, 2016 - Springer
The current epidemic affecting Indians is coronary artery disease (CAD), and is currently one
of the most common causes of mortality and morbidity in developed and developing …

Genetics of the quantitative Lp (a) lipoprotein trait: III. Contribution of Lp (a) glycoprotein phenotypes to normal lipid variation

E Boerwinkle, HJ Menzel, HG Kraft, G Utermann - Human genetics, 1989 - Springer
Summary Apolipoprotein (a)[apo (a)] is a large serum glycoprotein with several genetically
determined isoforms differing in their apparent molecular weight. We determined the effects …

A pentanucleotide repeat polymorphism in the 5'control region of the apolipoprotein (a) gene is associated with lipoprotein (a) plasma concentrations in Caucasians.

M Trommsdorff, S Köchl, A Lingenhel… - The Journal of …, 1995 - Am Soc Clin Investig
The enormous interindividual variation in the plasma concentrations of the atherogenic
lipoprotein (a)[Lp (a)] is almost entirely controlled by the apo (a) locus on chromosome 6q26 …

Apolipoprotein (a) gene accounts for greater than 90% of the variation in plasma lipoprotein (a) concentrations.

E Boerwinkle, CC Leffert, J Lin… - The Journal of …, 1992 - Am Soc Clin Investig
Plasma lipoprotein (a)[Lp (a)], a low density lipoprotein particle with an attached
apolipoprotein (a)[apo (a)], varies widely in concentration between individuals. These …