Many lung diseases are characterized by neutrophil-dominated inflammation; therefore, an
understanding of neutrophil function is of considerable importance to respiratory physicians …

Neutrophils are critical components of the body's immune response to infection, being
loaded with a potent arsenal of toxic mediators and displaying immense destructive …

Neutrophils are immune cells with unusual biological features that furnish potent
antimicrobial properties. These cells phagocytose and subsequently kill prokaryotic and …

Neutrophils have long been considered simple suicide killers at the bottom of the hierarchy
of the immune response. That view began to change 10–20 yr ago, when the sophisticated …

Infections, cardiovascular disease, and cancer are major causes of disease and death
worldwide. Neutrophils are inescapably associated with each of these health concerns, by …

Neutrophils, the most abundant circulating leukocyte, are critical for host defense.
Granulopoiesis is under the control of transcriptional factors and culminates in mature …

Neutrophils have long been viewed as the final effector cells of an acute inflammatory
response, with a primary role in the clearance of extracellular pathogens. However, more …

Neutrophils are the most abundant leukocytes in blood. From the circulation, they are quickly
mobilized to sites of inflammation and/or infection. At the affected tissues, neutrophils display …

The neutrophil, a short-lived effector leukocyte of the innate immune system best known for
its proteases and other degradative cargo, has unique, reciprocal physiological interactions …

The primary function of neutrophils in the innate immune response–to contain and kill
invading microbial pathogens–is achieved through a series of rapid and coordinated …