Abstract PO-016: Test-the-test: Clinical utility of comprehensive whole exome sequencing (WES) and RNA-seq for lymphoma patients

D Chihara, K Balakrishnan, G Masand… - Blood Cancer …, 2024 - AACR
Due to the rapidly evolving landscape of targeted therapies, there is an unmet need for
comprehensive molecular profiling to guide treatment decisions for lymphoma patients …

Test-the-test: Clinical utility of comprehensive whole exome sequencing (WES) and RNA-seq for lymphoma patients

D Chihara, K Balakrishnan, G Masand… - Cancer Research, 2024 - AACR
Background: Due to the rapidly evolving landscape of targeted therapies, there is an unmet
need for comprehensive molecular profiling to guide treatment decisions for patients with …

Test-the-Test: Clinical Utility of Comprehensive Whole Exome Sequencing and RNA-Seq for Patients with Lymphoma

D Chihara, K Balakrishnan, G Masand… - Blood, 2023 - Elsevier
Introduction Due to the rapidly evolving landscape of targeted therapies, there is an unmet
need for comprehensive molecular profiling to guide treatment decisions for patients with …

Multisite clinical cross-validation and variant interpretation of a next generation sequencing panel for lymphoid cancer prognostication

PJB Sabatini, J Bridgers, S Huang, G Downs… - Journal of Clinical …, 2024 - jcp.bmj.com
Aims Genomic sequencing of lymphomas is under-represented in routine clinical testing
despite having prognostic and predictive value. Clinical implementation is challenging due …

Next-generation sequencing for lymphomas: perfecting a pipeline for personalized pathobiologic and prognostic predictions

RS Ohgami, A Rosenwald, A Bagg - The Journal of Molecular …, 2018 - jmdjournal.org
CME Accreditation Statement: This activity (“JMD 2018 CME Program in Molecular
Diagnostics”) has been planned and implemented in accordance with the accreditation …

[HTML][HTML] An Open-Source Toolkit That Powers the Genome-Wide Analysis of Mature B-Cell Lymphomas (GAMBL) Project

K Dreval, BM Grande, H Winata, J Wong, L Sethi… - Blood, 2021 - Elsevier
Introduction: Genome-and transcriptome-wide analyses continue to enhance our
understanding of the molecular pathogenesis of cancer. In lymphomas, this has enabled the …

Clinical application of next generation sequencing in lymphoma

AJ Scott, MC Tokaz, M Shango, S Devata… - Leukemia & …, 2021 - Taylor & Francis
Successful treatment of relapsed/refractory and rare subtypes of lymphomas remains a
therapeutic challenge. Though the use of tumor profiling is increasing, little is described …

Inferred Gene Expression By Cell-Free DNA Profiling Allows Noninvasive Lymphoma Classification

JA Mutter, MS Esfahani, J Schroers-Martin, SK Alig… - Blood, 2023 - Elsevier
Background: Current diagnostic criteria for mature B-cell tumors require a combination of
histopathological, immunophenotypic, cytogenetic, and genetic evaluations on tissue biopsy …

[HTML][HTML] Exploring the potential of shallow whole-genome sequencing for diagnosis and disease monitoring of lymphoma in liquid biopsy

L Raman, M Van Der Linden, C De Vriendt… - Blood, 2019 - Elsevier
Authors 1-3: Contributed equally to this work Authors 8-9: Shared last author Background
Genetic material from aggressive B-cell lymphoma is typified by recurrent multiple somatic …

Molecular Profiling across Lymphoma Subtypes Using MSK-Impact Next Generation Sequencing

CL Batlevi, E Drill, M Okwali, R Ptashkin, PC Caron… - Blood, 2022 - ashpublications.org
Introduction: Few studies provide next-generation sequencing (NGS) based, clinical
genomic profiling across lymphoma subtypes using tumor and matched normal samples to …