Histone chaperones assist nucleosomal rearrangements to facilitate the passage of DNA
and RNA polymerases through chromatin. The FACT (fa cilitates c hromatin t ranscription) …

The histone chaperone FACT (FAcilitates Chromatin Transcription) modulates nucleosome
structure during many processes requiring access to chromatinized DNA. Here, we review …

Centromeres exert vital cellular functions in mitosis and meiosis. A specialized histone and
other chromatin-bound factors nucleate a dynamic protein assembly that is required for the …

The FACT complex is a conserved cofactor for RNA polymerase II elongation through
nucleosomes. FACT bears histone chaperone activity and contributes to chromatin integrity …

Maintenance of the correct level and organisation of nucleosomes is crucial for genome
function. Here, we uncover a role for a conserved bromodomain AAA‐ATP ase, Abo1, in the …

The FACT (FAcilitates Chromatin Transactions) complex influences transcription initiation
and enables passage of RNA polymerase (Pol) II through gene body nucleosomes during …

DNA accessibility to regulatory proteins is substantially influenced by nucleosome structure
and dynamics. The facilitates chromatin transcription (FACT) complex increases the …

Previous studies have identified single amino acid changes within either histone H3 or H4
(Sin− versions) that allow transcription in the absence of the yeast SWI–SNF complex. The …

Parental histone recycling is vital for maintaining chromatin-based epigenetic information
during replication, yet its underlying mechanisms remain unclear. Here, we uncover an …

Preservation of nucleosomes during replication has been extensively studied, while the
maintenance of nucleosomes during transcription has gotten less attention. The histone …