miRNA in Parkinson's disease: From pathogenesis to theranostic approaches

A Elangovan, D Venkatesan, P Selvaraj… - Journal of Cellular …, 2023 - Wiley Online Library
Parkinson's disease (PD) is an age associated neurological disorder which is specified by
cardinal motor symptoms such as tremor, stiffness, bradykinesia, postural instability, and non …

Dysregulated microRNAs in neural system: Implication in pathogenesis and biomarker development in Parkinson's disease

J Lu, Y Xu, Z Quan, Z Chen, Z Sun, H Qing - Neuroscience, 2017 - Elsevier
Parkinson's disease is a debilitating neurodegenerative movement disorder, characterized
by the progressive and selective loss of dopaminergic neurons located in the substantia …

MicroRNA dysregulation in Parkinson's disease: a narrative review

YH Nies, NH Mohamad Najib, WL Lim… - Frontiers in …, 2021 - frontiersin.org
Parkinson's disease (PD) is a severely debilitating neurodegenerative disease, affecting the
motor system, leading to resting tremor, cogwheel rigidity, bradykinesia, walking and gait …

MicroRNAs in the epigenetic regulation of disease progression in Parkinson's disease

SC Selvakumar, KA Preethi, D Tusubira… - Frontiers in Cellular …, 2022 - frontiersin.org
Parkinson's disease (PD) is a multifactorial neurodegenerative condition with symptoms
such as resting tremor, rigidity, bradykinesia (slowness of moment), and postural instability …

Aberrant expression of circulating MicroRNA leads to the dysregulation of alpha-synuclein and other pathogenic genes in Parkinson's disease

M Cai, S Chai, T Xiong, J Wei, W Mao, Y Zhu… - Frontiers in Cell and …, 2021 - frontiersin.org
A group of circulating microRNAs (miRNAs) have been implicated in the pathogenesis of
Parkinson's disease. However, a comprehensive study of the interactions between …

Involvement of miRNA on epigenetics landscape of Parkinson's disease: From pathogenesis to therapeutics

SN Uppala, KP Tryphena, P Naren, S Srivastava… - Mechanisms of Ageing …, 2023 - Elsevier
The development of novel therapeutics for the effective management of Parkinson's disease
(PD) is undertaken seriously by the scientific community as the burden of PD continues to …

Systemic analysis of miRNAs in PD Stress Condition: miR-5701 modulates mitochondrial–lysosomal cross talk to regulate neuronal death

P Prajapati, L Sripada, K Singh, M Roy, K Bhatelia… - Molecular …, 2018 - Springer
Parkinson's disease (PD) is complex neurological disorder and is prevalent in the elderly
population. This is primarily due to loss of dopaminergic neurons in the substantia nigra pars …

MicroRNAs play a role in Parkinson's disease by regulating microglia function: from pathogenetic involvement to therapeutic potential

S Li, G Bi, S Han, R Huang - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Parkinson's disease (PD) is a clinically common neurodegenerative disease of the central
nervous system (CNS) characterized by loss of dopamine neurons in the substantia nigra …

MicroRNA machinery in Parkinson's disease: a platform for neurodegenerative diseases

A Saghazadeh, N Rezaei - Expert Review of Neurotherapeutics, 2022 - Taylor & Francis
MicroRNAs (miRNAs) are noncoding RNAs that recognize their protein-coding target genes
and whereby subjugate them after transcription. Despite the infancy of this field of science …

Role of MicroRNAs in Parkinson's disease

SY Goh, YX Chao, ST Dheen, EK Tan… - International journal of …, 2019 - mdpi.com
Parkinson's disease (PD) is a disabling neurodegenerative disease that manifests with
resting tremor, bradykinesia, rigidity and postural instability. Since the discovery of …