Improved outcome after relapse in children with acute myeloid leukaemia

J Abrahamsson, N Clausen… - British journal of …, 2007 - Wiley Online Library
Summary In the Nordic Society for Paediatric Haematology and Oncology paediatric study
acute myeloid leukaemia (AML) 93, event‐free survival was 50% and overall survival was …

Outcome for children with relapsed acute myeloid leukaemia following initial therapy in the Medical Research Council (MRC) AML 10 trial

DKH Webb, K Wheatley, G Harrison, RF Stevens… - Leukemia, 1999 - nature.com
Abstract Between May 1988 and March 1995, 359 children with acute myeloid leukaemia
(AML) were treated in the MRC AML 10 trial. Three risk groups were identified based on …

Outcome after intensive reinduction therapy and allogeneic stem cell transplant in paediatric relapsed acute myeloid leukaemia

L Karlsson, E Forestier, H Hasle… - British journal of …, 2017 - Wiley Online Library
Summary Given that 30–40% of children with acute myeloid leukaemia (AML) relapse after
primary therapy it is important to define prognostic factors and identify optimal therapy. From …

Outcome of children with relapsed acute myeloid leukemia following initial therapy under the AML99 protocol

H Nakayama, K Tabuchi, A Tawa, I Tsukimoto… - International journal of …, 2014 - Springer
The outcomes of children with relapsed acute myeloid leukemia (AML) are known to be
poor, but remain obscure. We retrospectively analyzed 71 patients who had relapsed …

Survival following relapse in children with acute myeloid leukemia: a report from AML-BFM and COG

M Rasche, M Zimmermann, E Steidel, T Alonzo… - Cancers, 2021 - mdpi.com
Simple Summary Acute myeloid leukemia in children remains a difficult disease to cure
despite intensive therapies that push the limits of tolerability. Though the intent of initial …

How I treat paediatric relapsed acute myeloid leukaemia

G Kaspers - British journal of haematology, 2014 - Wiley Online Library
The prognosis of paediatric acute myeloid leukaemia (AML) has improved significantly over
the recent decades, but still about one‐third of patients relapse. These patients have a …

Outcome for children treated for relapsed or refractory acute myelogenous leukemia (rAML): a Therapeutic Advances in Childhood Leukemia (TACL) Consortium …

MF Gorman, L Ji, RH Ko, P Barnette… - Pediatric blood & …, 2010 - Wiley Online Library
Background Current event‐free survival (EFS) rates for children with newly diagnosed acute
myeloid leukemia (AML) approach 50–60%. We hypothesize that further improvements in …

Duration of first remission predicts remission rates and long-term survival in children with relapsed acute myelogenous leukemia

K Stahnke, J Boos, C Bender-Götze, J Ritter… - Leukemia, 1998 - nature.com
Although treatment of childhood acute myelogenous leukemia (AML) has substantially
improved in the last 15 years, in nearly half of the patients disease recurs. The aim of this …

A comparison of the outcomes of children with acute myelogenous leukemia in either first or second complete remission (CR1 vs CR2) following allogeneic …

A Gassas, MK Ishaqi, S Afzal… - Bone marrow …, 2008 - nature.com
We reviewed 70 consecutive children with AML who received hematopoietic stem cell
transplantation (HSCT) in our institution between 1994 and 2005. Forty-seven children were …

Outcome of children with acute myeloid leukaemia (AML) experiencing primary induction failure in the AIEOP AML 2002/01 clinical trial

P Quarello, F Fagioli, G Basso, MC Putti… - British Journal of …, 2015 - Wiley Online Library
Paediatric patients with acute myeloid leukaemia (AML) who fail induction due to primary
resistance to chemotherapy account for a significant proportion of cases and have a …