Diagnostic investigation and multidisciplinary management in motor neuron disease

JA Rocha, C Reis, F Simoes, J Fonseca… - Journal of …, 2005 - Springer
Amyotrophic lateral sclerosis (ALS) is the most common adult-onset motor neuron disease.
ALS is a progressive neurodegenerative disorder, involving motor neurons in the cerebral …

Amyotrophic lateral sclerosis

JS Salameh, RH Brown Jr, JD Berry - Seminars in neurology, 2015 - thieme-connect.com
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease primarily affecting the
upper and lower motor neurons. The lifetime risk of developing ALS is estimated at 1: 350 for …

Clinical diagnosis and management of amyotrophic lateral sclerosis

O Hardiman, LH Van Den Berg… - Nature reviews neurology, 2011 - nature.com
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that results in
progressive loss of bulbar and limb function. Patients typically die from respiratory failure …

Amyotrophic lateral sclerosis: clinical management and research update

J Andrews - Current neurology and neuroscience reports, 2009 - Springer
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that
selectively affects the motor neurons of the brain and spinal cord. ALS occurs in about 1 in …

Amyotrophic lateral sclerosis: pathophysiology, diagnosis and management

PH Gordon - CNS drugs, 2011 - Springer
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease associated
with a life expectancy of approximately 3 years after symptom onset, but the range of survival …

Current view and perspectives in amyotrophic lateral sclerosis

S Mathis, P Couratier, A Julian, P Corcia… - Neural Regeneration …, 2017 - journals.lww.com
Amyotrophic lateral sclerosis (ALS), identified as a distinct clinical entity by Charcot since the
end of the nineteenth century, is a devastating and fatal neurodegenerative disorder that …

Amyotrophic lateral sclerosis

LC Wijesekera, P Nigel Leigh - Orphanet journal of rare diseases, 2009 - Springer
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterised by
progressive muscular paralysis reflecting degeneration of motor neurones in the primary …

[HTML][HTML] Shortcomings in the current amyotrophic lateral sclerosis trials and potential solutions for improvement

N Katyal, R Govindarajan - Frontiers in neurology, 2017 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a clinically progressive neurodegenerative syndrome
predominantly affecting motor neurons and their associated tracts. Riluzole and edaravone …

Evaluation and rehabilitation of patients with adult motor neuron disease

K Francis, JR Bach, JA DeLisa - Archives of physical medicine and …, 1999 - Elsevier
Adult motor neuron disease (amyotrophic lateral sclerosis [Als]) is a neurodegenerative
disorder characterized by loss of motor neurons in the cortex, brain stem, and spinal cord …

Overview of motor neuron disease: classification and nomenclature.

WG Bradley - Clinical neuroscience (New York, NY), 1995 - europepmc.org
Amyotrophic lateral sclerosis (ALS), although a disease that has been well recognized for
nearly 150 years, still causes problems of diagnosis and management, as there is no …