Chondral Injury Associated With ACL Injury: Assessing Progressive Chondral Degeneration With Morphologic and Quantitative MRI Techniques

EJ Davidson, C Figgie, J Nguyen, V Pedoia… - Sports …, 2023 - journals.sagepub.com
Background: Anterior cruciate ligament (ACL) injuries are associated with a risk of post-
traumatic osteoarthritis due to chondral damage. Magnetic resonance imaging (MRI) …

Knee fibrosis is associated with the development of osteoarthritis in a murine model of tibial compression

M Wang, SG Lessard, P Singh… - Journal of …, 2021 - Wiley Online Library
Fibrosis in the synovium and infrapatellar fat pad (IFP) is frequently observed in knee
osteoarthritis (OA) and is often correlated with joint pain and stiffness. However, the …

[HTML][HTML] The Effects of an Osteoarthritic Joint Environment on ACL Damage and Degeneration: A Yucatan Miniature Pig Model

E Schwartz, K Chang, C Sun, F Zhang, G Peng… - Biomolecules, 2023 - mdpi.com
Posttraumatic osteoarthritis (PTOA) arises secondary to joint injuries and is characteristically
driven by inflammatory mediators. PTOA is often studied in the setting of ACL tears …

The infrapatellar fat pad contributes to spontaneous healing after complete anterior cruciate ligament injury

T Kano, Y Minegish, H Terada… - Experimental …, 2023 - journals.sagepub.com
Anterior cruciate ligament (ACL) injuries have a very low healing capacity but have recently
been shown to heal spontaneously with conservative treatment. This study examined the …

Alterations in Hoffa's fat pad induced by an inflammatory response following idealized anterior cruciate ligament surgery

NM Solbak, BJ Heard, Y Achari, M Chung… - Inflammation …, 2015 - Springer
Objective To determine whether inflammation following anterior cruciate ligament (ACL)
reconstruction leads to long-term pathological changes in the infrapatellar fat pad (IPFP or …

Infrapatellar fat pad volume and Hoffa‐synovitis after ACL reconstruction: Association with early osteoarthritis features and pain over 5 years

HF Hart, AG Culvenor, BE Patterson… - Journal of …, 2022 - Wiley Online Library
Infrapatellar fat pad (IPFP) morphology and Hoffa‐synovitis may be relevant to the
development and progression of post‐traumatic osteoarthritis (OA). We aimed to compare …

Effects of male and female sex on the development of posttraumatic osteoarthritis in the porcine knee after anterior cruciate ligament surgery

MP Pinette, J Molino, BL Proffen… - … American journal of …, 2022 - journals.sagepub.com
Background: Posttraumatic osteoarthritis (PTOA) is a common sequela of anterior cruciate
ligament (ACL) injury, even when surgical treatment is selected. The effect of patient sex on …

Traumatic joint injury induces acute catabolic bone turnover concurrent with articular cartilage damage in a rat model of posttraumatic osteoarthritis

T Maerz, MD Newton, M Fleischer… - Journal of …, 2021 - Wiley Online Library
Assess acute alterations in bone turnover, microstructure, and histomorphometry following
noninvasive anterior cruciate ligament rupture (ACLR). Twelve female Lewis rats were …

[HTML][HTML] Long-term periarticular bone adaptation in a feline knee injury model for post-traumatic experimental osteoarthritis

SK Boyd, R Müller, T Leonard, W Herzog - Osteoarthritis and cartilage, 2005 - Elsevier
OBJECTIVES: This study investigates the long-term changes of the periarticular bone,
including cancellous bone and the subchondral plate, in an anterior cruciate ligament (ACL) …

Effects of anterior cruciate ligament deficiency on tibiofemoral cartilage thickness and strains in response to hopping

EG Sutter, B Liu, GM Utturkar… - … American journal of …, 2019 - journals.sagepub.com
Background: Changes in knee kinematics after anterior cruciate ligament (ACL) injury may
alter loading of the cartilage and thus affect its homeostasis, potentially leading to the …