Objective This article addresses considerations for using a posterior (popliteal) instead of
anterior (para-patellar) approach for experimental insult to the rabbit knee medial femoral …

Background: Although patients with an anterior cruciate ligament (ACL) injury have a high
risk of developing posttraumatic osteoarthritis (PTOA), the role of meniscus hypertrophy and …

Osteoarthritis (OA) is a leading cause of disability worldwide. We hypothesized that
inflammation following isolated intra‐articular bone injury can stimulate post‐traumatic OA …

DISCUSSION In our experience, more than 80% of symptomatic chronic ACL-deficient
knees demonstrate regions of physiologically overstressed bone, probably secondary to …

Results: All animals exhibited a more painful joint on day 3 postinjection compared to day 0
(Fig. 1). Higher MIA dose caused more pain and greater gait alteration than the lower dose …

This study sought to develop a noninvasive, reliable, clinically relevant, and easy-to-
implement mouse model that can be used for investigation of the pathophysiology of PTOA …

Complications following anterior cruciate ligament (ACL) injury and reconstruction that
include chronic dysfunction, second ACL injury, and posttraumatic osteoarthritis (OA) may …

Background Animal models have long been considered an important modality for studying
ACL injuries. However, to our knowledge, the value of these preclinical models to study sex …

Objective: To identify demographic and anthropometric risk factors for intra-articular (IA)
injuries observed during ACL reconstruction. We hypothesize that significant associations …

Obesity and high body mass index are associated with a higher incidence of osteoarthritis
(OA). The aim of this study is to investigate the involvement of the infrapatellar fat pad (IPFP) …