Sample preparation remains a challenge in untargeted metabolomics studies and no
method currently results in complete extraction of all metabolite classes in human plasma …

The aim of metabolite profiling is to monitor all metabolites within a biological sample for
applications in basic biochemical research as well as pharmacokinetic studies and …

For the first time it is possible to simultaneously collect targeted and nontargeted
metabolomics data from plasma based on GC with high scan speed tandem mass …

Metabolome analysis using capillary electrophoresis (CE) coupled with high-resolution
mass spectrometry (HRMS) has the potential to improve coverage of metabolite detection …

This work aims at evaluating the relevance and versatility of liquid chromatography coupled
to high resolution mass spectrometry (LC/HRMS) for performing a qualitative and …

Rationale The metabolite profiling of a NIST plasma Standard Reference Material (SRM
1950) on different liquid chromatography/mass spectrometry (LC/MS) platforms showed …

In this paper, we describe data processing and metabolite identification approaches which
lead to a rapid and semi-automated interpretation of metabolomics experiments. Data from …

A method for the preparation and GC− TOF-MS analysis of human serum samples has been
developed and evaluated for application in long-term metabolomic studies. Serum samples …

Blood is widely used for discovery metabolomics to search for disease biomarkers.
However, blood sample matrix can have a profound effect on metabolome analysis, which …

Metabolism has an essential role in biological systems. Identification and quantitation of the
compounds in the metabolome is defined as metabolic profiling, and it is applied to define …