High-resolution mass spectrometry (HRMS)-based metabolomics approaches have made
significant advances. However, metabolite identification is still a major challenge with …

Recent advances in mass spectrometry are enabling improved analysis of endogenous
metabolites. Here we discuss several issues relevant to developing liquid chromatography …

Metabolomics is the comprehensive assessment of endogenous metabolites and attempts to
systematically identify and quantify metabolites from a biological sample. Small-molecule …

The choice of sample-preparation method is extremely important in metabolomic studies
because it affects both the observed metabolite content and biological interpretation of the …

Recently, metabolomics analyses have become increasingly common in the general
scientific community as it is applied in several researches relating to diseases diagnosis …

Recently, the use of metabolomic analysis of human serum and plasma for biomarker
discovery and disease diagnosis in clinical studies has been increasing. The feasibility of …

Sample preparation is the gateway to metabolomic analysis, the importance of which cannot
be overemphasized. There are general rules of thumb for sample preparation that help …

Mass Spectrometry-Based Metabolomics: A Practical Guide is a simple, step-by-step
reference for profiling metabolites in a target organism. It discusses optimization of sample …

Introduction Global metabolomics analyses using body fluids provide valuable results for the
understanding and prediction of diseases. However, the mechanism of a disease is often …

Sample preparation plays a critical role in untargeted profiling of biological fluids and tissues
by nuclear magnetic resonance and mass spectrometry for biomarker discovery. In this …