Cell-based high-throughput screening is a key step in the current disease-based research,
drug development, and precision medicine. However, it is challenging to establish a rapid …

Precision oncology aims to tailor clinical decisions specifically to patients with the objective
of improving treatment outcomes. This can be achieved by leveraging omics information for …

Despite its high potential, PD-L1 expressed by tumors has not been successfully utilized as
a biomarker for estimating treatment responses to immunotherapy. Circulating tumor cells …

Effective isolation and in-depth analysis of Circulating Tumour Cells (CTCs) are greatly
needed in diagnosis, prognosis and monitoring of the therapeutic response of cancer …

Understanding the underlying mechanisms of migration and metastasis is a key focus of
cancer research. There is an urgent need to develop in vitro 3D tumor models that can mimic …

Integrating clinical rare cell enrichment, culture, and single-cell phenotypic profiling is
currently hampered by the lack of competent technologies, which typically suffer from weak …

Recent research suggests that cancer stem-like cells (CSCs) are the key subpopulation for
tumor relapse and metastasis. Due to cancer plasticity in surface antigen and enzymatic …

Similar to healthy tissues, many blood and solid malignancies are now thought to be
organised hierarchically, with a subset of stem-like cancer cells that self-renew while giving …

Cell spheroids are multicellular aggregates, grown in vitro, that mimic the three-dimensional
morphology of physiological tissues. Although there are numerous benefits to using …

Liquid marbles are exploited in this study as efficient miniature bioreactors inoculated with
Hep G2 (hepatocellular carcinoma) cells to culture cell spheroids in vitro. This method …