The CB1 cannabinoid receptor mediates excitotoxicity-induced neural progenitor proliferation and neurogenesis
Endocannabinoids are lipid signaling mediators that exert an important neuromodulatory
role and confer neuroprotection in several types of brain injury. Excitotoxicity and stroke can …
role and confer neuroprotection in several types of brain injury. Excitotoxicity and stroke can …
Non‐psychoactive CB2 cannabinoid agonists stimulate neural progenitor proliferation
J Palazuelos, T Aguado, A Egia… - The FASEB …, 2006 - Wiley Online Library
Cannabinoids, the active components of marijuana and their endogenous counterparts, act
on the brain and many other organs through the widely expressed CB1 cannabinoid …
on the brain and many other organs through the widely expressed CB1 cannabinoid …
Cannabinoids promote oligodendrocyte progenitor survival: involvement of cannabinoid receptors and phosphatidylinositol-3 kinase/Akt signaling
E Molina-Holgado, JM Vela… - Journal of …, 2002 - Soc Neuroscience
Cannabinoids exert pleiotropic actions in the CNS, including the inhibition of inflammatory
responses and the enhancement of neuronal survival after injury. Although cannabinoid …
responses and the enhancement of neuronal survival after injury. Although cannabinoid …
Type-1 (CB1) Cannabinoid Receptor Promotes Neuronal Differentiation and Maturation of Neural Stem Cells
C Compagnucci, S Di Siena, MB Bustamante… - PloS one, 2013 - journals.plos.org
Neural stem cells (NSCs) are self-renewing cells that can differentiate into multiple neural
lineages and repopulate regions of the brain after injury. We have investigated the role of …
lineages and repopulate regions of the brain after injury. We have investigated the role of …
CB1 cannabinoid receptors increase neuronal precursor proliferation through AKT/glycogen synthase kinase-3β/β-catenin signaling
The endocannabinoid system is involved in the regulation of many physiological effects in
the central and peripheral nervous system. Recent findings have demonstrated the …
the central and peripheral nervous system. Recent findings have demonstrated the …
CB2 cannabinoid receptors promote neural progenitor cell proliferation via mTORC1 signaling
J Palazuelos, Z Ortega, J Díaz-Alonso… - Journal of Biological …, 2012 - ASBMB
The endocannabinoid system is known to regulate neural progenitor (NP) cell proliferation
and neurogenesis. In particular, CB 2 cannabinoid receptors have been shown to promote …
and neurogenesis. In particular, CB 2 cannabinoid receptors have been shown to promote …
Mechanisms of control of neuron survival by the endocannabinoid system
I Galve-Roperh, T Aguado… - Current …, 2008 - ingentaconnect.com
Endocannabinoids act as retrograde messengers that, by inhibiting neurotransmitter release
via presynaptic CB1 cannabinoid receptors, regulate the functionality of many synapses. In …
via presynaptic CB1 cannabinoid receptors, regulate the functionality of many synapses. In …
The endocannabinoid system promotes astroglial differentiation by acting on neural progenitor cells
Endocannabinoids exert an important neuromodulatory role via presynaptic cannabinoid
CB1 receptors and may also participate in the control of neural cell death and survival. The …
CB1 receptors and may also participate in the control of neural cell death and survival. The …
Endocannabinoids: a new family of lipid mediators involved in the regulation of neural cell development
I Galve-Roperh, T Aguado, D Rueda… - Current …, 2006 - ingentaconnect.com
The endocannabinoids (eCBs) anandamide and 2-arachidonoylglycerol are important
retrograde messengers that inhibit neurotransmitter release via presynaptic CB1 receptors …
retrograde messengers that inhibit neurotransmitter release via presynaptic CB1 receptors …
The endocannabinoid anandamide inhibits neuronal progenitor cell differentiation through attenuation of the Rap1/B-Raf/ERK pathway
D Rueda, B Navarro, A Martı́nez-Serrano… - Journal of Biological …, 2002 - ASBMB
Endocannabinoids are neuromodulators that act as retrograde synaptic messengers
inhibiting the release of different neurotransmitters in cerebral areas such as hippocampus …
inhibiting the release of different neurotransmitters in cerebral areas such as hippocampus …