This review describes the IL-20 family of cytokines in rheumatoid arthritis (RA) and
spondyloartrhitits (SpA) including psoriatic arthritis. The IL-20 receptor (R) cytokines IL-19, IL …

The IL-12 family members, IL-12, IL-23, IL-27 and IL-35, are heterodimeric cytokines that
share subunits and have important roles in autoimmunity. As well as their structural …

Rheumatoid arthritis, a systemic autoimmune disease, causes chronic joint inflammation
and bone destruction. Interleukin (IL)-20's association with this disease, and its expression …

Rheumatoid arthritis (RA) is an autoimmune, chronic inflammatory disease and is
characterized by destruction of the articular cartilage. A number of pro-inflammatory …

The discovery that the IL-23–IL-17 immune pathway is involved in many models of
autoimmune disease has changed the concept of the role of T-helper cell subsets in the …

The development of innovative technologies is steadily increasing the body of knowledge on
molecules involved in physiological functions. Thus, several interleukins (ILs) have been …

Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by synovial
inflammation and resultant progressive joint damage. It has become increasingly evident …

Background Rheumatoid arthritis (RA) is often characterized by the presence of rheumatoid
factor, anti-citrullinated protein antibodies, and bone erosions. Current therapies can …

Two heterodimeric receptors consisting of either IL-20R1 or IL-22R1 in complex with a
common β receptor subunit IL-20R2 are shared by three of the IL-20 family of cytokines: IL …

Interleukin 17 is a proinflammatory cytokine produced by CD4+ T cells when in the presence
of a distinct set of cytokines and other cells. Preclinical and clinical studies have assigned a …