Molecular genetics of lipoprotein (a): new pieces to the puzzle
A Gaw, HH Hobbs - Current opinion in lipidology, 1994 - journals.lww.com
Important advances have been made in the past year in our understanding of the genetics of
lipoprotein (a)[Lp (a)]. The apolipoprotein (a)[APO (a)] gene has been cloned and mice have …
lipoprotein (a)[Lp (a)]. The apolipoprotein (a)[APO (a)] gene has been cloned and mice have …
Studies on the structure and function of the apolipoprotein (a) gene
CD Byrne, RM Lawn - Clinical genetics, 1994 - Wiley Online Library
Lp (a) is an LDL‐like lipoprotein that is a major inherited risk factor for atherosclerosis. It is
distinguished from Lp (a) by the addition of apolipoprotein (a). The gene structure of …
distinguished from Lp (a) by the addition of apolipoprotein (a). The gene structure of …
Lipoprotein (a) in homozygous familial hypercholesterolemia
HG Kraft, A Lingenhel, FJ Raal… - … , and vascular biology, 2000 - Am Heart Assoc
Lipoprotein (a)[Lp (a)] is a quantitative genetic trait that in the general population is largely
controlled by 1 major locus—the locus for the apolipoprotein (a)[apo (a)] gene. Sibpair …
controlled by 1 major locus—the locus for the apolipoprotein (a)[apo (a)] gene. Sibpair …
[引用][C] Genetic architecture of the atherogenic lipoprotein (a)
G Utermann, C Haibach, M Trommsdorff… - Annals of the New …, 1994 - Wiley Online Library
Lipoprotein (a)[Lp (a)] is a quantitative genetic trait in human plasma that is almost
unaffected by age, diet, or life-style. Thc distribution of Lp (a) plasma concentrations is …
unaffected by age, diet, or life-style. Thc distribution of Lp (a) plasma concentrations is …
The apolipoprotein (a) gene resides on human chromosome 6q26–27, in close proximity to the homologous gene for plasminogen
SL Frank, I Klisak, RS Sparkes, T Mohandas… - Human genetics, 1988 - Springer
Summary Apolipoprotein (a)[apo (a)], the glycoprotein associated with the lipoprotein (a)[Lp
(a)] subfraction of plasma lipoproteins, has been shown to exhibit heritable molecular weight …
(a)] subfraction of plasma lipoproteins, has been shown to exhibit heritable molecular weight …
Genetics of plasma lipoprotein (a) concentrations
E Boerwinkle - Current Opinion in Lipidology, 1992 - journals.lww.com
Abstract Lipoprotein (a)[Lp (a)] is a low-density-like lipoprotein with the addition of a Lp (a)-
specific protein, apolipoprotein (a)[apo (a)]. Plasma concentrations of Lp (a) are a risk factor …
specific protein, apolipoprotein (a)[apo (a)]. Plasma concentrations of Lp (a) are a risk factor …
The apolipoprotein (a) gene: a transcribed hypervariable locus controlling plasma lipoprotein (a) concentration
HG Kraft, S Köchl, HJ Menzel, C Sandholzer… - Human genetics, 1992 - Springer
Abstract Lipoprotein (a)[Lp (a)] is a quantitative trait in human plasma. Lp (a) consists of a
low-density lipoprotein and the plasminogen-related apolipoprotein (a)[apo (a)]. The apo (a) …
low-density lipoprotein and the plasminogen-related apolipoprotein (a)[apo (a)]. The apo (a) …
Genetic variation in lipoprotein (a) levels in families enriched for coronary artery disease is determined almost entirely by the apolipoprotein (a) gene locus.
CA DeMeester, X Bu, RJ Gray, AJ Lusis… - American journal of …, 1995 - ncbi.nlm.nih.gov
Abstract Lipoprotein (a)(Lp [a]) is a cholesterol-rich lipoprotein resembling LDL but also
containing a large polypeptide designated apolipoprotein (a)(apo [a]). Its levels are highly …
containing a large polypeptide designated apolipoprotein (a)(apo [a]). Its levels are highly …
Molecular basis for “null” lipoprotein (a) phenotypes and the influence of apolipoprotein (a) size on plasma lipoprotein (a) level in the baboon.
AL White, JE Hixson, DL Rainwater… - Journal of Biological …, 1994 - Elsevier
High plasma levels of lipoprotein (a)(Lp (a)) and its unique apolipoprotein, apo (a), are an
independent risk factor for cardiovascular disease. Plasma Lp (a) levels vary over a 1000 …
independent risk factor for cardiovascular disease. Plasma Lp (a) levels vary over a 1000 …
Structure, function, and genetics of lipoprotein (a)
K Schmidt, A Noureen, F Kronenberg… - Journal of lipid …, 2016 - ASBMB
Lipoprotein (a)[Lp (a)] has attracted the interest of researchers and physicians due to its
intriguing properties, including an intragenic multiallelic copy number variation in the LPA …
intriguing properties, including an intragenic multiallelic copy number variation in the LPA …