Polyphenolic coumpounds in Chemoprevention of colon cancer-Targets and signaling pathways

E Rudolf, H Andelova… - Anti-Cancer Agents in …, 2007 - ingentaconnect.com
Colorectal cancer is one of the leading causes of premature death in people worldwide. Due
to the fact that malignant conversion of normal colonic cells requires several steps and often …

Polyphenols in colorectal cancer: current state of knowledge including clinical trials and molecular mechanism of action

MN Alam, M Almoyad, F Huq - BioMed research international, 2018 - Wiley Online Library
Polyphenols have been reported to have wide spectrum of biological activities including
major impact on initiation, promotion, and progression of cancer by modulating different …

Greasing the Wheels of Pharmacotherapy for Colorectal Cancer: The Role of Natural Polyphenols

C Niu, J Zhang, P Okolo - Current Nutrition Reports, 2023 - Springer
Abstract Purpose of Review The main purpose of this review, mainly based on preclinical
studies, is to summarize the pharmacological and biochemical evidence regarding natural …

[HTML][HTML] Natural polyphenols: A protective approach to reduce colorectal cancer

J Okpoghono, EF Isoje, UA Igbuku, O Ekayoda… - Heliyon, 2024 - cell.com
Background A form of cancer that affects the rectum or colon (large intestine) is called
colorectal cancer (CRC). The main risk factors for CRC include dietary, lifestyle, and …

[HTML][HTML] Natural polyphenols for treatment of colorectal cancer

Y Zhang, K Liu, C Yan, Y Yin, S He, L Qiu, G Li - Molecules, 2022 - mdpi.com
Colorectal cancer (CRC) is a prevalent and serious gastrointestinal malignancy with high
mortality and morbidity. Chemoprevention refers to a newly emerged strategy that uses …

[HTML][HTML] Natural polyphenols as targeted modulators in colon cancer: molecular mechanisms and applications

J Long, P Guan, X Hu, L Yang, L He, Q Lin… - Frontiers in …, 2021 - frontiersin.org
Colon cancer commonly develops from long-term chronic inflammation in the intestine and
seriously threatens human health. Natural polyphenols have been valued as a crucial …

[HTML][HTML] Polyphenols: immunomodulatory and therapeutic implication in colorectal cancer

AM Mileo, P Nisticò, S Miccadei - Frontiers in immunology, 2019 - frontiersin.org
Polyphenolic compounds, widely present in fruits, vegetables, and cereals, have potential
benefits for human health and are protective agents against the development of …

[HTML][HTML] Phenolic phytochemicals for prevention and treatment of colorectal cancer: A critical evaluation of in vivo studies

S De, S Paul, A Manna, C Majumder, K Pal, N Casarcia… - Cancers, 2023 - mdpi.com
Simple Summary Colorectal cancer (CRC) is a significant cause of death worldwide. The
inefficacy of the current treatment regimens is reflected in the frequent recurrence and …

Cancer chemoprevention and chemotherapy: dietary polyphenols and signalling pathways

S Ramos - Molecular nutrition & food research, 2008 - Wiley Online Library
Prevention of cancer through dietary intervention recently has received an increasing
interest, and dietary polyphenols have become not only important potential …

[HTML][HTML] The protective effect of polyphenols for colorectal cancer

S Ding, S Xu, J Fang, H Jiang - Frontiers in immunology, 2020 - frontiersin.org
Colorectal cancer (CRC) is one of the most prevalent cancers that threaten people in many
countries. It is a multi-factorial chronic disease caused by a combination of genetic and …