To investigate the long-term effects of Helicobacter pylori gastritis on the gastric mucosa, 13
wild Japanese monkeys (six H. pylori-infected and seven controls) were monitored for 5 …

Background: Helicobacter pylori infection is associated with gastroduodenal disease in
humans. In this study we aimed to show this relationship directly in Mongolian gerbils …

We have established a Helicobacter pylori-infected Mongolian gerbil model, following
Hirayama's method, to clarify gastric diseases associated with H. pylori infection. We …

Objectives: To assess the suitability of an established experimental model for chronic
gastritis associated with Helicobacter pylori for use in long-term observations. Design: In a 3 …

Helicobacter pylori is considered to have a close association with gastric cancer. Many
epidemiological studies have shown a strong association between chronic H. pylori infection …

Many epidemiological studies have shown a strong association between chronic
Helicobacter pylori infection and the subsequent development of gastric carcinoma in …

Background & Aims: Although epidemiological studies have indicated that Helicobacter
pylori infection plays a crucial role in gastric carcinogenesis in humans, there is no direct …

Helicobacter pylori has been recognized as a pathogen causing gastroduodenal disease,
with adequate evidence to prove this relation in clinical research. Available animal models …

We used Japanese monkeys (Macaca fuscata) to establish an experimental model in order
to clarify the pathogenicity of Helicobacter pylori in gastric and duodenal disorders. A …

A Mongolian gerbil model was used to clarify whether long-term colonization by
Helicobacter pylori is an important risk factor for the development of gastric cancer. Fifty-nine …