Background. Silent infarcts have been reported in 17% of young patients with sickle cell
disease and are associated with impaired performance on standardized psychometric tests …

Objective: To determine whether children with homozygous sickle cell anemia (SCD) who
have silent infarcts on magnetic resonance imaging (MRI) of the brain are at increased risk …

Silent cerebral infarct (SCI) is the most common form of neurologic disease in children with
sickle cell anemia (SCA). SCI is defined as abnormal magnetic resonance imaging (MRI) of …

Silent infarcts have been reported most commonly in school‐aged children with
homozygous sickle cell disease (SCD‐SS) and are associated with neurocognitive deficits …

We hypothesized that the silent cerebral infarcts (SCI), which affect up to 40% of children
with sickle cell disease (SCD), could occur in the setting of acute anemic events. In a …

Children with sickle cell anemia (HbSS) are at high risk for neurologically overt cerebral
infarcts associated with stroke and neurologically silent cerebral infarcts correlated with …

Background Silent cerebral infarcts are the most common neurologic injury in children with
sickle cell anemia and are associated with the recurrence of an infarct (stroke or silent …

Background Irregular, sporadic episodes of ischemic brain injury are known to occur in
sickle cell anemia (SCA), resulting in overt stroke and silent cerebral infarction. Ongoing …

The most common form of neurologic injury in sickle cell anemia (SCA) is silent cerebral
infarction (SCI). In the Silent Cerebral Infarct Multi-Center Clinical Trial, we sought to identify …

Much progress has been made during the past several decades in gaining understanding
about the natural history of sickle cell disease and management approaches aimed at …