Insight into the processes controlling adipogenesis is important in the battle against the
obesity epidemic and its related disorders. The transcriptional regulatory cascade involved …

Genome-wide DNA methylation has been implicated in complex human diseases. Here, we
identified epigenetic biomarkers for type 2 diabetes (T2D) underlying obesogenic …

Background Obesity is a major health problem that is determined by interactions between
lifestyle and environmental and genetic factors. Although associations between several …

Epigenetic mechanisms, including DNA methylation, mediate the interaction between gene
and environment and may play an important role in the obesity epidemic. We assessed the …

Aims/hypothesis Epigenetic alterations may influence the metabolic pathways involved in
human obesity. We hypothesised that global DNA methylation levels in adipose tissue might …

Epigenetic modifications have been highlighted in chronic non-communicable diseases.
The aim of this study was to investigate genome-wide DNA methylation for the identification …

Background We conducted an epigenome-wide association study (EWAS) on obesity in
healthy youth and young adults and further examined to what extent identified signals …

Background Epigenome-wide association studies of human disease and other quantitative
traits are becoming increasingly common. A series of papers reporting age-related changes …

Aim: Validation of epigenome-wide association studies is sparse. Therefore, we evaluated
the methylation markers cg06500161 (ABCG1) and cg11024682 (SREBF1) as classifiers for …

Here, we performed a genome-wide search for methylation sites that contribute to the risk of
obesity. We integrated methylation quantitative trait locus (mQTL) data with BMI GWAS …