Background Epigenetics can contribute to lipid disorders in obesity. The DNA methylation
pattern can be the cause or consequence of high blood lipids. The aim of the study was to …

We conducted an epigenome-wide association study on obesity-related traits. We used data
from 2 prospective, population-based cohort studies: the Rotterdam Study (RS)(2006–2013) …

Here, we performed a genome-wide search for methylation sites that contribute to the risk of
obesity. We integrated methylation quantitative trait locus (mQTL) data with BMI GWAS …

The extent to which genetic influences on cardiovascular disease risk are mediated by
changes in DNA methylation levels has not been systematically explored. We developed an …

Over the past 50 years, the number of overweight/obese people increased significantly,
making obesity a global public health challenge. Apart from rare monogenic forms, obesity is …

Background Epigenetic changes in visceral adipose tissue (VAT) with obesity and their
effects on gene expression are poorly understood, especially during emergent obesity in …

Epigenetic processes such as dynamic promoter methylation may play a role in obesity, fat
distribution and its accompanied metabolic alterations. TMEM18 is a candidate gene for …

Purpose Epigenetic signatures such as DNA methylation may be associated with specific
obesity traits. We performed an epigenome-wide association study (EWAS) by combining …

Background DNA methylation is a key epigenetic mechanism that is suggested to be
associated with blood lipid levels. We aimed to identify CpG sites at which DNA methylation …

Background: Association studies of epigenome-wide DNA methylation and disease can
inform biological mechanisms. DNA methylation is often measured in peripheral blood, with …