[HTML][HTML] Conflict in the Intracellular Lives of Endosymbionts and Viruses: A Mechanistic Look at Wolbachia-Mediated Pathogen-blocking

ARI Lindsey, T Bhattacharya, ILG Newton, RW Hardy - Viruses, 2018 - mdpi.com
At the forefront of vector control efforts are strategies that leverage host-microbe associations
to reduce vectorial capacity. The most promising of these efforts employs Wolbachia, a …

Wolbachia as translational science: controlling mosquito-borne pathogens

EP Caragata, HLC Dutra, PHF Sucupira… - Trends in …, 2021 - cell.com
In this review we examine how exploiting the Wolbachia–mosquito relationship has become
an increasingly popular strategy for controlling arbovirus transmission. Field deployments of …

Understanding the Wolbachia-mediated inhibition of arboviruses in mosquitoes: progress and challenges

SM Rainey, P Shah, A Kohl… - Journal of General …, 2014 - microbiologyresearch.org
Arthropod-borne viruses (arboviruses) pose a considerable threat to human and animal
health, yet effective control measures have proven difficult to implement, and novel means of …

Wolbachia-Conferred Antiviral Protection Is Determined by Developmental Temperature

E Chrostek, N Martins, MS Marialva, L Teixeira - MBio, 2021 - Am Soc Microbiol
Wolbachia is a maternally transmitted bacterium that is widespread in arthropods and filarial
nematodes and confers strong antiviral protection in Drosophila melanogaster and other …

[HTML][HTML] Viral RNA is a target for Wolbachia-mediated pathogen blocking

T Bhattacharya, ILG Newton, RW Hardy - PLoS Pathogens, 2020 - journals.plos.org
The ability of the endosymbiont Wolbachia pipientis to restrict RNA viruses is presently
being leveraged to curb global transmission of arbovirus-induced diseases. Past studies …

[HTML][HTML] A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodium

LA Moreira, I Iturbe-Ormaetxe, JA Jeffery, G Lu… - Cell, 2009 - cell.com
Wolbachia are maternally inherited intracellular bacterial symbionts that are estimated to
infect more than 60% of all insect species. While Wolbachia is commonly found in many …

Sustained Wolbachia-mediated blocking of dengue virus isolates following serial passage in Aedes aegypti cell culture

C Koh, MD Audsley, F Di Giallonardo, EJ Kerton… - Virus …, 2019 - academic.oup.com
Wolbachia is an intracellular endosymbiont of insects that inhibits the replication of a range
of pathogens in its arthropod hosts. The release of Wolbachia into wild populations of …

[HTML][HTML] Exploiting intimate relationships: controlling mosquito-transmitted disease with Wolbachia

EP Caragata, HLC Dutra, LA Moreira - Trends in parasitology, 2016 - cell.com
Mosquito-transmitted diseases impose a growing burden on human health, and current
control strategies have proven insufficient to stem the tide. The bacterium Wolbachia is a …

[HTML][HTML] The Antiviral Effects of the Symbiont Bacteria Wolbachia in Insects

AC Pimentel, CS Cesar, M Martins… - Frontiers in immunology, 2021 - frontiersin.org
Wolbachia is a maternally transmitted bacterium that lives inside arthropod cells. Historically,
it was viewed primarily as a parasite that manipulates host reproduction, but more recently it …

[HTML][HTML] Symbionts Commonly Provide Broad Spectrum Resistance to Viruses in Insects: A Comparative Analysis of Wolbachia Strains

J Martinez, B Longdon, S Bauer, YS Chan… - PLoS …, 2014 - journals.plos.org
In the last decade, bacterial symbionts have been shown to play an important role in
protecting hosts against pathogens. Wolbachia, a widespread symbiont in arthropods, can …