Protein corona change the drug release profile of nanocarriers: the “overlooked” factor at the nanobio interface
S Behzadi, V Serpooshan, R Sakhtianchi… - Colloids and Surfaces B …, 2014 - Elsevier
The emergence of nanocarrier systems in drug delivery applications has ushered in rapid
development of new classes of therapeutic agents which can provide an essential …
development of new classes of therapeutic agents which can provide an essential …
Controlling the stealth effect of nanocarriers through understanding the protein corona
S Schöttler, K Landfester… - Angewandte Chemie …, 2016 - Wiley Online Library
The past decade has seen a significant increase in interest in the use of polymeric
nanocarriers in medical applications. In particular, when used as drug vectors in targeted …
nanocarriers in medical applications. In particular, when used as drug vectors in targeted …
The effects of protein corona on in vivo fate of nanocarriers
With the emerging advances in utilizing nanocarriers for biomedical applications, a
molecular-level understanding of the in vivo fate of nanocarriers is necessary. After …
molecular-level understanding of the in vivo fate of nanocarriers is necessary. After …
Understanding and utilizing the biomolecule/nanosystems interface
Combining biomolecules with materials used in medicine allows for local control of the
biological response and can be used for modulating the host immune response, a major …
biological response and can be used for modulating the host immune response, a major …
Unveiling the pitfalls of the protein corona of polymeric drug nanocarriers
The protein corona is a natural protein layer spontaneously formed around nanomaterials
when exposed to biological media. This layer can alter the nanosystems' biological …
when exposed to biological media. This layer can alter the nanosystems' biological …
Biomolecular corona on nanoparticles: a survey of recent literature and its implications in targeted drug delivery
RM Pearson, VV Juettner, S Hong - Frontiers in chemistry, 2014 - frontiersin.org
Achieving controlled cellular responses of nanoparticles (NP) is critical for the successful
development and translation of NP-based drug delivery systems. However, precise control …
development and translation of NP-based drug delivery systems. However, precise control …
Biomolecular corona affects controlled release of drug payloads from nanocarriers
Nanomedicine has been widely used for a wide range of biomedical applications including
drug delivery. Although many factors including the physicochemical properties of …
drug delivery. Although many factors including the physicochemical properties of …
In vitro-in vivo correlation in nanocarriers: From protein corona to therapeutic implications
Understanding and establishing a link between the physicochemical characteristics of
nanoparticles (NPs) and their biological interactions poses to be a great challenge in the …
nanoparticles (NPs) and their biological interactions poses to be a great challenge in the …
The impact of protein corona on the biological behavior of targeting nanomedicines
For successful translation of targeting nanomedicines from bench to bedside, it is vital to
address their most common drawbacks namely rapid clearance and off-target accumulation …
address their most common drawbacks namely rapid clearance and off-target accumulation …
Temperature, concentration, and surface modification influence the cellular uptake and the protein corona of polystyrene nanoparticles
J Oberländer, C Champanhac, R da Costa Marques… - Acta Biomaterialia, 2022 - Elsevier
The composition of the protein corona varies depending on several parameters and
influences the cellular fate of the nanocarriers. Here, we investigated the influence of three …
influences the cellular fate of the nanocarriers. Here, we investigated the influence of three …
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