Protein corona change the drug release profile of nanocarriers: the “overlooked” factor at the nanobio interface

S Behzadi, V Serpooshan, R Sakhtianchi… - Colloids and Surfaces B …, 2014 - Elsevier
The emergence of nanocarrier systems in drug delivery applications has ushered in rapid
development of new classes of therapeutic agents which can provide an essential …

Controlling the stealth effect of nanocarriers through understanding the protein corona

S Schöttler, K Landfester… - Angewandte Chemie …, 2016 - Wiley Online Library
The past decade has seen a significant increase in interest in the use of polymeric
nanocarriers in medical applications. In particular, when used as drug vectors in targeted …

The effects of protein corona on in vivo fate of nanocarriers

Q Xiao, M Zoulikha, M Qiu, C Teng, C Lin, X Li… - Advanced Drug Delivery …, 2022 - Elsevier
With the emerging advances in utilizing nanocarriers for biomedical applications, a
molecular-level understanding of the in vivo fate of nanocarriers is necessary. After …

Understanding and utilizing the biomolecule/nanosystems interface

EY Chen, WF Liu, L Megido, P Díez, M Fuentes… - … in preventive and …, 2018 - Elsevier
Combining biomolecules with materials used in medicine allows for local control of the
biological response and can be used for modulating the host immune response, a major …

Unveiling the pitfalls of the protein corona of polymeric drug nanocarriers

G Berrecoso, J Crecente-Campo, MJ Alonso - Drug delivery and …, 2020 - Springer
The protein corona is a natural protein layer spontaneously formed around nanomaterials
when exposed to biological media. This layer can alter the nanosystems' biological …

Biomolecular corona on nanoparticles: a survey of recent literature and its implications in targeted drug delivery

RM Pearson, VV Juettner, S Hong - Frontiers in chemistry, 2014 - frontiersin.org
Achieving controlled cellular responses of nanoparticles (NP) is critical for the successful
development and translation of NP-based drug delivery systems. However, precise control …

Biomolecular corona affects controlled release of drug payloads from nanocarriers

S Sharifi, G Caracciolo, M Mahmoudi - Trends in pharmacological sciences, 2020 - cell.com
Nanomedicine has been widely used for a wide range of biomedical applications including
drug delivery. Although many factors including the physicochemical properties of …

In vitro-in vivo correlation in nanocarriers: From protein corona to therapeutic implications

TG Agnihotri, A Alexander, M Agrawal… - Journal of Controlled …, 2023 - Elsevier
Understanding and establishing a link between the physicochemical characteristics of
nanoparticles (NPs) and their biological interactions poses to be a great challenge in the …

The impact of protein corona on the biological behavior of targeting nanomedicines

M Farshbaf, H Valizadeh, Y Panahi, Y Fatahi… - International Journal of …, 2022 - Elsevier
For successful translation of targeting nanomedicines from bench to bedside, it is vital to
address their most common drawbacks namely rapid clearance and off-target accumulation …

Temperature, concentration, and surface modification influence the cellular uptake and the protein corona of polystyrene nanoparticles

J Oberländer, C Champanhac, R da Costa Marques… - Acta Biomaterialia, 2022 - Elsevier
The composition of the protein corona varies depending on several parameters and
influences the cellular fate of the nanocarriers. Here, we investigated the influence of three …