The focus of this thesis is $\beta $-tubulin gene function, the regulation of $\beta $-tubulin
expression, and $\beta $-tubulin secondary modifications in the ciliated protozoan …

The ciliate Tetrahymena pyriformis contains one α‐tubulin (αTT) and two β‐tubulin (βTT1
and βTT2) genes. The specific expression of these genes was investigated by Northern blot …

This thesis describes the functional analysis of the β-like tubulin gene, BLT1, in T.
thermophila. BLT1 encodes a highly divergent β-tubulin isotype; it has only 66% identity to …

This thesis focuses on functional studies of tubulins in Tetrahymena. $\gamma $-Tubulin, a
new member of tubulin superfamily with important function for microtubule nucleation, was …

The single alpha‐tubulin gene of Tetrahymena thermophila was isolated from a genomic
library and shown to encode a single protein. Comparisons of the rates of evolution of this …

Background The multi-tubulin hypothesis proposes that each tubulin isotype performs a
unique role, or subset of roles, in the universe of microtubule function (s). To test this …

Background: The multi-tubulin hypothesis proposes that each tubulin isotype performs a
unique role, or subset of roles, in the universe of microtubule function (s). To test this …

The mechanisms that regulate γ‐tubulin, including its post‐translational modifications, are
poorly understood. γ‐Tubulin is important for the duplication of centrioles and structurally …

Macronuclear DNA of the ciliate Tetrahymena pyriformis contains only one size class of
fragments coding for α-tubulin, αTT. We have isolated αTT from a partial plasmid library …

Unlike higher eukaryotes with typically large tubulin multigene families (about 12 genes),
Tetrahymena provides a rare opportunity to study tubulin in an organism with a complex …