Alzheimer's disease (AD) is a progressive, dementing, whole-body disorder that presents
with decline in cognitive, behavioral, and emotional functions, as well as endocrine …

Exposure to chronic stress or elevated glucocorticoid hormone levels in adult life has been
associated with cognitive deficits and an increased risk for Alzheimer's disease (AD). Since …

Alzheimer's disease (AD) is often accompanied by changes in mood as well as increases in
circulating cortisol levels, suggesting that regulation of the stress responsive hypothalamic …

Elevated cortisol evidence in Alzheimer's disease (AD) patients prompted the hypothesis
that stress and glucocorticoids are involved in the development and/or maintenance of AD …

In this study, we investigated mice of the TgCRND8 line, an APP transgenic mouse model of
Alzheimer's disease (AD), with respect to behavioral, endocrinological, and …

Memory impairment in Alzheimer's disease patients is thought to be associated with the
accumulation of amyloid-beta peptides and tau proteins. However, inconsistent reports of …

Differences in brain function are a central determinant of individual variability in the stress
response. Brain dysfunction, resulting from aging, illness, or genetic mutations, could reduce …

Activation of the hypothalamic-pituitary-adrenal (HPA) axis occurs in response to the
organism's innate need for homeostasis. The glucocorticoids (GCs) that are released into …

Neuropsychiatric disturbances (NPDs) are considered hallmarks of Alzheimer's disease
(AD). Nevertheless, treatment of these symptoms has proven difficult and development of …

Stress confers risk for the development and progression of Alzheimer's disease (AD).
Relative to men, women are disproportionately more likely to be diagnosed with this …