Rationale Different lines of evidence suggest that mitochondrial dysfunction may be
implicated in bipolar disorder (BD) pathophysiology. Mitochondrial electron transport chain …

Bipolar disorder (BD) is one of the major psychiatric diseases in which the impairment of
mitochondrial functions has been closely connected or associated with the disease …

The understanding of the pathophysiology of bipolar disorder (BD) remains modest, despite
recent advances in neurobiological research. The mitochondrial dysfunction hypothesis of …

Bipolar disorder is a common, chronic, and complex mental illness. Bipolar disorder is
frequently comorbid with primary mitochondrial and metabolic disorders, and studies have …

Background Mitochondrial dysfunctions are implicated in the pathophysiology of mood
disorders. We measured and examined the following selected mitochondrial parameters …

Background Bipolar disorder (BD) is a chronic and recurrent disease characterized by acute
mood episodes and periods of euthymia. The available literature postulates that a biphasic …

Background Evidence supports the role for mitochondrial impairment in the pathophysiology
of bipolar disorder (BD). BD has been associated with decreased mitochondrial electron …

Objectives: Extensive preclinical and clinical evidence suggests mitochondrial dysfunction in
bipolar disorder. Studies of brain energy metabolism in bipolar disorder suggest an …

Although evidence for mitochondrial dysfunction in the pathogenesis of bipolar disorder
(BD) has been reported, the precise biological basis remains unknown, hampering the …

Evidence suggests that mitochondrial dysfunction is involved in the pathophysiology of
psychiatric disorders such as schizophrenia (SZ) and bipolar disorder (BD). However, the …