[HTML][HTML] Mesenchymal stem cell-loaded thermosensitive hydroxypropyl chitin hydrogel combined with a three-dimensional-printed poly (ε-caprolactone)/nano …

X Ji, X Yuan, L Ma, B Bi, H Zhu, Z Lei, W Liu, HX Pu… - Theranostics, 2020 - ncbi.nlm.nih.gov
Chitin-derived hydrogels are commonly used in bone regeneration because of their high cell
compatibility; however, their poor mechanical properties and little knowledge of the …

Temperature-and pH-responsive chitosan-based injectable hydrogels for bone tissue engineering

K Lavanya, SV Chandran, K Balagangadharan… - Materials Science and …, 2020 - Elsevier
Spontaneous bone regeneration is heavily restricted because of bone defects, and external
mediation is required to enhance repair and regeneration. Bone tissue engineering (BTE) is …

Hydroxyethyl chitosan-reinforced polyvinyl alcohol/biphasic calcium phosphate hydrogels for bone regeneration

L Nie, Y Deng, P Li, R Hou, A Shavandi, S Yang - Acs Omega, 2020 - ACS Publications
Fabrication of reinforced scaffolds for bone regeneration remains a significant challenge.
The weak mechanical properties of the chitosan (CS)-based composite scaffold hindered its …

Injectable chitosan hydrogel embedding modified halloysite nanotubes for bone tissue engineering

F Kazemi-Aghdam, V Jahed, M Dehghan-Niri… - Carbohydrate …, 2021 - Elsevier
Low mechanical strength and untargeted osteoinduction of chitosan hydrogel limit its
application for bone regeneration. This study aimed to develop an injectable chitosan …

Thermosensitive injectable hydrogel based on chitosan-polygalacturonic acid polyelectrolyte complexes for bone tissue engineering

GK Wasupalli, D Verma - Carbohydrate Polymers, 2022 - Elsevier
An extracellular matrix (ECM) mimicking a 3D microenvironment is an essential requirement
to achieve desirable repair or regeneration of damaged tissue or organ. In this context …

Biocompatibility evaluation of chitosan-based injectable hydrogels for the culturing mice mesenchymal stem cells in vitro

J Yan, L Yang, G Wang, Y Xiao… - Journal of …, 2010 - journals.sagepub.com
A thermosensitive polymer can be held liquid before being injected to deliver living cells or
therapeutic agents and formed monolithic gels when injected in vivo. In this study, chitosan …

Nanohydroxyapatite-reinforced chitosan composite hydrogel for bone tissue repair in vitro and in vivo

S Dhivya, S Saravanan, TP Sastry… - Journal of …, 2015 - Springer
Background Bone loss during trauma, surgeries, and tumor resection often results in critical-
sized bone defects that need to be filled with substitutionary materials. Complications …

Chitosan/hydroxyapatite nanocomposite scaffolds to modulate osteogenic and inflammatory response

A Soriente, I Fasolino… - … Research Part A, 2022 - Wiley Online Library
Considerable attention has been given to the use of chitosan (CS)‐based materials
reinforced with inorganic bioactive signals such as hydroxyapatite (HA) to treat bone defects …

[HTML][HTML] Cartilage repair mediated by thermosensitive photocrosslinkable TGFβ1-loaded GM-HPCH via immunomodulating macrophages, recruiting MSCs and …

X Ji, Z Lei, M Yuan, H Zhu, X Yuan, W Liu, H Pu… - Theranostics, 2020 - ncbi.nlm.nih.gov
Repairing cartilage defects using thermosensitive hydrogels is an attractive treatment
strategy, but the poor mechanical properties and limited understanding of the interactions …

Hydroxyapatite-integrated, heparin-and glycerol-functionalized chitosan-based injectable hydrogels with improved mechanical and proangiogenic performance

FZ Kocak, M Yar, IU Rehman - International Journal of Molecular …, 2022 - mdpi.com
The investigation of natural bioactive injectable composites to induce angiogenesis during
bone regeneration has been a part of recent minimally invasive regenerative medicine …