Cost-effectiveness analysis of the first-line EGFR-TKIs in patients with non-small cell lung cancer harbouring EGFR mutations

MS Holleman, MJ Al, R Zaim, HJM Groen… - The European Journal of …, 2020 - Springer
Objectives To compare the cost-effectiveness of first-line gefitinib, erlotinib, afatinib, and
osimertinib in patients with non-small cell lung cancer (NSCLC) harbouring epidermal …

Cost-effectiveness analysis of osimertinib for first-line treatment of locally advanced or metastatic EGFR mutation positive non-small cell lung cancer in Singapore

MIA Aziz, WYX Foo, CK Toh, WT Lim… - Journal of medical …, 2020 - Taylor & Francis
Objective Non-small cell lung cancer (NSCLC) accounts for 80–90% of all lung cancer
cases and is usually associated with a poor prognosis. However, targeted therapy with first …

Cost-effectiveness of osimertinib versus standard EGFR-TKI as first-line treatment for locally advanced or metastatic EGFR mutation-positive non-small cell lung …

T Khoo, L Gao - Expert review of pharmacoeconomics & outcomes …, 2021 - Taylor & Francis
Objectives: To assess the cost-effectiveness of osimertinib versus standard epidermal
growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), gefitinib or erlotinib, as first …

Budget impact of sequential treatment with first-line afatinib versus first-line osimertinib in non-small-cell lung cancer patients with common EGFR mutations

L Westerink, JLJ Nicolai, C Samuelsen… - The European Journal of …, 2020 - Springer
Background The therapeutic landscape for non-small-cell lung cancer (NSCLC) patients that
have common epidermal growth factor receptor (EGFR) mutations has changed radically in …

Cost‐effectiveness of osimertinib in treating newly diagnosed, advanced EGFR‐mutation‐positive non‐small cell lung cancer

B Wu, X Gu, Q Zhang, F Xie - The Oncologist, 2019 - academic.oup.com
Background The objective of this study was to assess cost and effectiveness of osimertinib in
treating newly diagnosed advanced non‐small cell lung cancer with an epidermal growth …

Cost-effectiveness of afatinib, gefitinib, erlotinib and pemetrexed-based chemotherapy as first-line treatments for advanced non-small cell lung cancer in China

X Gu, Q Zhang, YB Chu, YY Zhao, YJ Zhang, D Kuo… - Lung Cancer, 2019 - Elsevier
Purpose Tyrosine kinase inhibitors (TKI) of the epidermal growth factor receptor (EGFR) are
becoming the standard treatments for Chinese patients with advanced non-small cell lung …

Cost-effectiveness of osimertinib in the first-line treatment of patients with EGFR-mutated advanced non–small cell lung cancer

PN Aguiar, B Haaland, W Park, P San Tan… - JAMA …, 2018 - jamanetwork.com
Importance The survival of patients with advanced non–small cell lung cancer (NSCLC) with
epidermal growth factor receptor (EGFR) gene mutations has improved substantially in the …

Cost-effectiveness of osimertinib in the UK for advanced EGFR-T790M non-small cell lung cancer

E Bertranou, C Bodnar, V Dansk… - Journal of Medical …, 2018 - Taylor & Francis
Aim: This study presents the cost-utility analysis that was developed to inform the NICE
health technology assessment of osimertinib vs platinum-based doublet chemotherapy …

[HTML][HTML] Economic analysis of first-line treatment with erlotinib in an EGFR-mutated population with advanced NSCLC

A Vergnenegre, B Massuti, F de Marinis… - Journal of Thoracic …, 2016 - Elsevier
Introduction The cost-effectiveness of first-line tyrosine kinase inhibitor therapy in epidermal
growth factor receptor gene (EGFR)-mutated advanced-stage non–small cell lung cancer …

[HTML][HTML] Cost-effectiveness of osimertinib for EGFR mutation–positive non–small cell lung cancer after progression following first-line EGFR TKI therapy

B Wu, X Gu, Q Zhang - Journal of Thoracic Oncology, 2018 - Elsevier
Objective The aim of this study was to investigate the cost-effectiveness of osimertinib for the
treatment of advanced NSCLC with an EGFR T790M mutation after the failure of first-line …