Abstract Background and Aim Interleukin (IL)-1 family members play an important role in the
pathogenesis of inflammatory bowel disease (IBD). There are conflicting results regarding …

Objectives: It is aimed to determine the association between four single-nucleotide
polymorphisms (SNPs) of IL1 genes (rs1800587: IL1A− 889 C/T, rs16944: IL1B− 511 T/C …

The two major types of IBD are ulcerative colitis (UC) and Crohn's disease (CD), whose
etiology involves immunological and environmental factors. CD and UC share some …

BACKGROUND: Several studies have tried to find possible associations between genetic
polymorphisms and inflammatory bowel disease prevalence and/or phenotype. Our …

Objective To investigate the association of interleukin 8 (IL-8) gene polymorphisms with the
risks of inflammatory bowel disease (IBD). Methods Single nucleotide polymorphisms …

1. Introduction. Multiple cytokines have been studied for their role in the propagation of the
inflammatory process related to inflammatory bowel diseases (IBD), but the role of …

Background: Changes in cytokine expression have been frequently found in patients with
inflammatory bowel disease (IBD). Cytokine values outside the normal range may be …

Abstract Objective Inflammatory bowel diseases (IBDs), namely ulcerative colitis (UC) and
Crohn's disease (CD), are characterized by chronic and idiopathic inflammatory conditions …

Background & Aims: The role of the interleukin (IL)-1 receptor antagonist (IL-1ra) in
predisposing an individual to inflammatory bowel disease (IBD) is controversial. This study …

Inflammatory bowel disease (IBD), which includes Crohn's disease (CD) and ulcerative
colitis (UC), represents a group of chronic inflammatory disorders caused by dysregulated …