[HTML][HTML] Tumor metabolic reprogramming by adipokines as a critical driver of obesity-associated cancer progression

DV Pham, PH Park - International journal of molecular sciences, 2021 - mdpi.com
Adiposity is associated with an increased risk of various types of carcinoma. One of the
plausible mechanisms underlying the tumor-promoting role of obesity is an aberrant …

[HTML][HTML] Targeting adipokines in obesity-related tumors

X Pu, D Chen - Frontiers in Oncology, 2021 - frontiersin.org
Obesity, a global epidemic, is an independent risk factor for the occurrence and
development of a variety of tumors, such as breast cancer, pancreatic cancer, ovarian …

Adipose tissue dysfunction and its effects on tumor metabolism

J Diedrich, HC Gusky, I Podgorski - Hormone molecular biology and …, 2015 - degruyter.com
Growing by an alarming rate in the Western world, obesity has become a condition
associated with a multitude of diseases such as diabetes, metabolic syndrome and various …

Adipocytes: impact on tumor growth and potential sites for therapeutic intervention

S Hefetz-Sela, PE Scherer - Pharmacology & therapeutics, 2013 - Elsevier
The prevalence of obesity has increased dramatically in recent decades, reaching epidemic
proportions. It is becoming clear that obesity is associated not only with type 2 diabetes …

Insights into the link between obesity and cancer

SE Ackerman, OA Blackburn, F Marchildon… - Current obesity …, 2017 - Springer
Abstract Purpose of Review Adipocytes have adapted to store energy in the form of lipid and
also secrete circulating factors called adipokines that signal to other tissues to coordinate …

Classic and novel adipocytokines at the intersection of obesity and cancer: diagnostic and therapeutic strategies

N Spyrou, KI Avgerinos, CS Mantzoros… - Current obesity …, 2018 - Springer
Abstract Purpose of Review In this review, we investigate the role of classic and novel
adipocytokines in cancer pathogenesis synopsizing the mechanisms underlying the …

[HTML][HTML] Adipose tissue, obesity and adipokines: role in cancer promotion

A Booth, A Magnuson, J Fouts… - … molecular biology and …, 2015 - degruyter.com
Adipose tissue is a complex organ with endocrine, metabolic and immune regulatory roles.
Adipose depots have been characterized to release several adipocytokines that work locally …

[HTML][HTML] Multi‑faceted role of cancer‑associated adipocytes in the tumor microenvironment

H Yao, S He - Molecular Medicine Reports, 2021 - spandidos-publications.com
Adipocytes are a type of stromal cell found in numerous different tissues that serve an active
role in the tumor microenvironment. Cancer‑associated adipocytes (CAAs) display a …

[HTML][HTML] Role of obesity-associated dysfunctional adipose tissue in cancer: a molecular nutrition approach

PL Prieto-Hontoria, P Pérez-Matute… - … et Biophysica Acta (BBA …, 2011 - Elsevier
Obesity is a complex disease caused by the interaction of a myriad of genetic, dietary,
lifestyle and environmental factors, which favors a chronic positive energy balance, leading …

Obesity and cancer: the role of dysfunctional adipose tissue

RCM Van Kruijsdijk, E Van Der Wall… - … , biomarkers & prevention, 2009 - AACR
Overweight and obesity are health problems of epidemic proportions, increasing the risk not
only of cardiovascular disease and type 2 diabetes mellitus but also of various types of …