Molecular mechanisms underlying chemopreventive potential of curcumin: Current challenges and future perspectives

G Kumar, S Mittal, K Sak, HS Tuli - Life sciences, 2016 - Elsevier
In recent years, natural compounds have received considerable attention in preventing and
curing most dreadful diseases including cancer. The reason behind the use of natural …

[HTML][HTML] The multifaceted role of curcumin in cancer prevention and treatment

MK Shanmugam, G Rane, MM Kanchi, F Arfuso… - Molecules, 2015 - mdpi.com
Despite significant advances in treatment modalities over the last decade, neither the
incidence of the disease nor the mortality due to cancer has altered in the last thirty years …

Curcumin: a potential candidate in prevention of cancer via modulation of molecular pathways

AH Rahmani, MA Al Zohairy, SM Aly… - BioMed research …, 2014 - Wiley Online Library
Cancer is the most dreadful disease worldwide in terms of morbidity and mortality. The exact
cause of cancer development and progression is not fully known. But it is thought that cancer …

Curcumin in cancer chemoprevention: molecular targets, pharmacokinetics, bioavailability, and clinical trials

A Shehzad, F Wahid, YS Lee - Archiv der Pharmazie, 2010 - Wiley Online Library
Curcumin (diferuloylmethane), a derivative of turmeric is one of the most commonly used
and highly researched phytochemicals. Abundant sources provide interesting insights into …

Molecular mechanisms of curcumin action: signal transduction

A Shehzad, YS Lee - Biofactors, 2013 - Wiley Online Library
Chemoprevention represents one of the most highly effective anti‐cancer strategies and is
accompanied by minimal secondary effects as compared to conventional chemotherapies …

Multiple molecular targets in cancer chemoprevention by curcumin

RL Thangapazham, A Sharma, RK Maheshwari - The AAPS journal, 2006 - Springer
Carcinogenesis encompasses 3 closely associated stages: initiation, progression, and
promotion. Phytochemicals are nonnutritive components of plants that are currently being …

[HTML][HTML] Curcumin a potent cancer preventive agent: Mechanisms of cancer cell killing

M Tuorkey - Interventional Medicine and Applied Science, 2014 - akjournals.com
There is no doubt that diet could effectively improve health and halt cancers. Dietary
phytochemical compounds and their derivatives represent a cornucopia of effectively …

New perspectives of curcumin in cancer prevention

W Park, ARMR Amin, ZG Chen, DM Shin - Cancer prevention research, 2013 - AACR
Numerous natural compounds have been extensively investigated for their potential for
cancer prevention over the decades. Curcumin, from Curcuma longa, is a highly promising …

Curcumin in various cancers

A Shehzad, J Lee, YS Lee - Biofactors, 2013 - Wiley Online Library
Curcumin (diferuloylmethane), an active constituent of turmeric, is a well‐described
phytochemical, which has been used since ancient times for the treatment of various …

[HTML][HTML] Potential mechanisms of action of curcumin for cancer prevention: focus on cellular signaling pathways and miRNAs

M Wang, S Jiang, L Zhou, F Yu, H Ding… - … journal of biological …, 2019 - ncbi.nlm.nih.gov
Despite significant progressions in treatment modalities over the last decade, either cancer
incidence or mortality is continuously on the rise throughout the world. Current anticancer …