Structure-based inhibition of acetylcholinesterase and butyrylcholinesterase with 2-Aryl-6-carboxamide benzoxazole derivatives: synthesis, enzymatic assay, and in …
An important research topic is the discovery of multifunctional compounds targeting different
disease-causing components. This research aimed to design and synthesize a series of 2 …
disease-causing components. This research aimed to design and synthesize a series of 2 …
Development of promising acetylcholinesterase and butyrylcholinesterase inhibitors: Synthesis, in vitro and in silico approaches of pyridine derived fused bis …
The present study aims to synthesize new thiadiazole/oxadiazole fused thiadiazole
derivatives, incorporating pyridine moiety as effective inhibitors of acetylcholinesterase …
derivatives, incorporating pyridine moiety as effective inhibitors of acetylcholinesterase …
Synthesis and AChE-inhibitory activity of new benzimidazole derivatives
Alzheimer's disease (AD), one of the main causes of aged dementia, is a progressive and
degenerative neurological disorder characterized by loss of cognition and memory …
degenerative neurological disorder characterized by loss of cognition and memory …
Multipotent cholinesterase inhibitors for the treatment of Alzheimer's disease: Synthesis, biological analysis and molecular docking study of benzimidazole-based …
Twenty-four analogues of benzimidazole-based thiazoles (1–24) were synthesized and
assessed for their in vitro acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) …
assessed for their in vitro acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) …
New biologically potent benzimidazole‐based‐triazole derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors along with molecular docking study
A series of fifteen hybrid analogs (1–15) based on benzimidazole bearing triazole skeleton
were synthesized and were evaluated for in vitro AChE and BuChE inhibition profile. All the …
were synthesized and were evaluated for in vitro AChE and BuChE inhibition profile. All the …
[HTML][HTML] Novel 1, 2, 4-oxadiazole derivatives as selective butyrylcholinesterase inhibitors: Design, synthesis and biological evaluation
M Nazari, E Rezaee, R Hariri, T Akbarzadeh… - EXCLI …, 2021 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a progressive mental disorder that brings a huge economic
burden to the healthcare systems. During this illness, acetylcholine levels in the cholinergic …
burden to the healthcare systems. During this illness, acetylcholine levels in the cholinergic …
Design, Synthesis, In Vitro Biological Evaluation and In Silico Molecular Docking Study of Benzimidazole-Based Oxazole Analogues: A Promising …
Alzheimer's disease (AD) is a degenerative neurological condition that severely affects the
elderly and is clinically recognised by a decrease in cognition and memory. The treatment of …
elderly and is clinically recognised by a decrease in cognition and memory. The treatment of …
Molecular modeling, synthesis, and in vitro acetylcholinesterase and butyrylcholinesterase inhibitory activities of novel benzimidazole-bearing thiadiazole derivatives
A new series of benzimidazole-based thiadiazole hybrids analogues (6a–p) as effective
Alzheimer's inhibitors were synthesized and then evaluated for their inhibition profile against …
Alzheimer's inhibitors were synthesized and then evaluated for their inhibition profile against …
Evaluation of novel dual Acetyl-and butyrylcholinesterase inhibitors as potential anti-Alzheimer's disease agents using pharmacophore, 3D-QSAR and molecular …
X Pang, H Fu, S Yang, L Wang, AL Liu, S Wu, GH Du - Molecules, 2017 - mdpi.com
DL0410, containing biphenyl and piperidine skeletons, was identified as an
acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitor through high …
acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitor through high …
Design, Synthesis and Anticholinesterase Activity of Coumarin‐1, 3, 5‐triazine Derivatives
XQ Zhang, J Wang, JP Zou, Y Cao, XH Xu… - …, 2024 - Wiley Online Library
Abstract A series of coumarin‐1, 3, 5‐triazine derivatives were designed, synthesized and
evaluated as acetylcholinesterase inhibitors. The structures of those compounds were …
evaluated as acetylcholinesterase inhibitors. The structures of those compounds were …
相关搜索
- acetylcholinesterase and butyrylcholinesterase benzoxazole derivatives
- acetylcholinesterase and butyrylcholinesterase enzymatic assay
- enzymatic assay benzoxazole derivatives
- butyrylcholinesterase inhibitors triazole derivatives
- oxazole analogues design synthesis
- thiazole derivatives cholinesterase inhibitors
- butyrylcholinesterase inhibitors silico approaches
- inhibition of acetylcholinesterase benzoxazole derivatives
- inhibition of acetylcholinesterase enzymatic assay