Chronic myelogenous leukemia (CML) is a malignant disease of the human hematopoietic
stem cell. The disease is characterized by an abnormal expansion of granulocytic …

Chronic myelogenous leukemia (CML) originates in a pluripotent hematopoetic stem cell of
the bone marrow and is characterized by greatly increased numbers of granulocytes in the …

Chronic myelogenous leukemia (CML) is a malignant disorder of the human hematopoietic
stem cell95 characterized by the Philadelphia chromosome (Ph). 195,222 The disease …

DATA SOURCES: Current literature. DATA SYNTHESIS: Chronic myelocytic leukemia
(CML) was initially described in 1845 and is considered one of the first leukemias to be …

Chronic myelogenous leukemia (CML) is a clonal neoplasm of the pluripotent hematopoietic
stem cell that is characterized by a consistent cytogenetic abnormality known as the …

Chronic myelogenous leukemia (CML) is a myeloproliferative disorder that follows a
characteristic clinical course in which a chronic phase of variable duration precedes an …

Chronic myeloid leukemia (CML) is probably the most extensively studied human
malignancy. The discovery of the Philadelphia (Ph) chromosome in 19601 as the first …

Chronic myeloid leukaemia (CML) is a relatively well defined disorder that accounts for 10 to
15% of all cases of leukaemia. It is thought to arise as a result of an acquired genetic change …

With an annual incidence of about ten in 1,000,000 people, chronic myeloid leukemia (CML)
accounts for most cases of myeloproliferative disease and for 20% of all leukemias. While …

Despite recent advances in our understanding of the molecular and biological abnormalities
in chronic myelogenous leukemia (CML) this new knowledge has not yet led to significant …