Delayed neutrophil apoptosis is a feature of persistent acute inflammation.
Neutrophilmediated damage has been shown to be associated with the development of …

The intestinal tract is a site of intense immune cell activity that is poised to mount an effective
response against a pathogen and yet maintain tolerance toward commensal bacteria and …

Background Reduced apoptosis of neutrophil granulocytes (PMN) contributes to
pathogenesis of systemic inflammatory response syndrome, sepsis, and multiple organ …

Cells of the intestinal mucosa live in a harsh environment and therefore rely heavily on the
highly regulated process of cell death, apoptosis, to maintain tissue integrity. Imbalance in …

Background and aims Abnormal apoptosis may result in the persistence of activated
intestinal T-cells in inflammatory bowel disease (IBD). We investigated apoptosis in distinct …

Delayed neutrophil apoptosis and overshooting neutrophil activity contribute to organ
dysfunction and subsequent organ failure in sepsis. Here, we investigated apoptotic …

As an essential part of programmed cell death, pyroptosis is an inflammatory response that
is elicited upon infection by intracellular pathogens. Metabolic diseases, atherosclerosis and …

Caspases are a group of proteolytic enzymes involved in the co-ordination of cellular
processes, including cellular homeostasis, inflammation and apoptosis. Altered activity of …

Background & Aims: Treatment with a chimeric anti-tumor necrosis factor (TNF) antibody
(infliximab) has been shown to be highly efficient for patients with steroid-refractory Crohn's …

PURPOSE: Because increased enterocyte apoptosis has been associated with the
pathogenesis of several chronic inflammatory diseases, the aim of our study was to …