Cancer cells employ both conventional oxidative metabolism and glycolytic anaerobic
metabolism. However, their proliferation is marked by a shift towards increasing glycolytic …

In the 1920s, Otto Warburg observed the phenomenon of altered glucose metabolism in
cancer cells. Although the initial hypothesis suggested that the alteration resulted from …

Previously, we identified a form of epithelial-stromal metabolic coupling, in which cancer
cells induce aerobic glycolysis in adjacent stromal fibroblasts, via oxidative stress, driving …

The Warburg effect in 2012 : Current Opinion in Oncology The Warburg effect in 2012 : Current
Opinion in Oncology Log in or Register Subscribe to journalSubscribe Get new issue alertsGet …

Cancer can be envisioned as a metabolic disease driven by pressure selection and
intercellular cooperativeness. Together with anaerobic glycolysis, the Warburg effect …

Cancer cells have been shown to have altered metabolism when compared to normal non-
malignant cells. The Warburg effect describes a phenomenon in which cancer cells …

The Warburg effect is a phenomenon in which cancer cells rely primarily on glycolysis rather
than oxidative phosphorylation, even in the presence of oxygen. Although evidence of its …

Tumor cells rely mainly on glycolysis for energy production even in the presence of sufficient
oxygen, a phenomenon termed the Warburg effect, which is the most outstanding …

Several decades ago, Otto Warburg discovered that cancer cells produce energy
predominantly by glycolysis; a phenomenon now termed “Warburg effect”. Warburg linked …

The Warburg effect describes the increased utilization of glycolysis rather than oxidative
phosphorylation by tumour cells for their energy requirements under physiological oxygen …