The renin-angiotensin system (RAS) plays a major role in the pathophysiology of
cardiovascular disorders. Angiotensin II (Ang-II), the final product of this pathway, is known …

The renin–angiotensin system (RAS) has pivotal roles in the regulation of normal physiology
and the pathogenesis of cardiovascular disease. Angiotensin-converting enzyme (ACE) 2 …

Angiotensin-converting enzyme 2 (ACE2) is a monocarboxypeptidase that metabolizes
several vasoactive peptides, including angiotensin II (Ang-II; a vasoconstrictive/proliferative …

Abstract Angiotensin II (Ang II), a bioactive peptide of the renin–angiotensin system (RAAS),
plays an important role in the development of cardiovascular diseases (CVD) …

Abstract Angiotensin-converting enzyme 2 (ACE2) is a monocarboxypeptidase that
metabolizes several peptides, including the degradation of angiotensin (Ang) II, a peptide …

Heart failure (HF) remains the most common cause of death and disability, and a major
economic burden, in industrialized nations. Physiological, pharmacological, and clinical …

The renin‐angiotensin system (RAS) is a critical regulator of hypertension, primarily through
the actions of the vasoactive peptide Ang II, which is generated by the action of angiotensin …

Importance of the field: The renin-angiotensin system (RAS) is nowadays an important target
in cardiovascular diseases and we are currently on the verge of a new interpretation of its …

Angiotensin-converting enzyme 2 (ACE2) is a recently discovered homologue of the key
enzyme of the renin-angiotensin system, the angiotensin-converting enzyme. The ACE2 …

Despite reduction in cardiovascular (CV) events and end‐organ damage with the current
pharmacologic strategies, CV disease remains the primary cause of death in the world …