MicroRNAs as biomarkers and therapeutic drugs in human cancer
M Osaki, F Takeshita, T Ochiya - Biomarkers, 2008 - Taylor & Francis
MicroRNAs (miRNAs) are evolutionarily conserved, endogenous, noncoding small RNAs
that act as post-transcriptional gene regulators. Experimental evidence has shown that …
that act as post-transcriptional gene regulators. Experimental evidence has shown that …
miR-143 is downregulated in cervical cancer and promotes apoptosis and inhibits tumor formation by targeting Bcl-2
Abstract microRNAs (miRNAs) are small non-coding RNA molecules of 21-24 nt that
regulate the expression of other genes by transcriptional inhibition or translational …
regulate the expression of other genes by transcriptional inhibition or translational …
Potential role of microRNAs in the treatment and diagnosis of cervical cancer
S Shen, S Zhang, P Liu, J Wang, H Du - Cancer genetics, 2020 - Elsevier
Invasive cervical cancer is a leading cause of cancer death in women worldwide. miRNA
may have roles in the pathogenesis of cervical cancer based on the increases or decreases …
may have roles in the pathogenesis of cervical cancer based on the increases or decreases …
MicroRNA expression signatures in solid malignancies
An ongoing challenge in cancer research is represented by the identification of new specific
clinical molecular markers and pharmacological targets. During the last 10 years …
clinical molecular markers and pharmacological targets. During the last 10 years …
MicroRNA expression and function in cancer
MicroRNAs are small non-coding RNAs of 19–24 nucleotides in length that downregulate
gene expression during various crucial cell processes such as apoptosis, differentiation and …
gene expression during various crucial cell processes such as apoptosis, differentiation and …
[HTML][HTML] MicroRNAs as markers of progression in cervical cancer: a systematic review
B Pardini, D De Maria, A Francavilla, C Di Gaetano… - BMC cancer, 2018 - Springer
Background Invasive cervical cancer (ICC) is caused by high-risk human papillomavirus
types (HR-HPVs) and is usually preceded by a long phase of intraepithelial neoplasia (CIN) …
types (HR-HPVs) and is usually preceded by a long phase of intraepithelial neoplasia (CIN) …
Altered microRNA expression associated with chromosomal changes contributes to cervical carcinogenesis
SM Wilting, PJF Snijders, W Verlaat, A Jaspers… - Oncogene, 2013 - nature.com
Little is known about the alterations in microRNA (miRNA) expression patterns during the
consecutive stages of cervical cancer development and their association with chromosomal …
consecutive stages of cervical cancer development and their association with chromosomal …
MicroRNA-133b is a key promoter of cervical carcinoma development through the activation of the ERK and AKT1 pathways
We report that elevated microRNA-133b (miR-133b) acts as an oncogene in human cervical
carcinoma to promote tumorigenesis and metastasis. In situ hybridization confirmed that miR …
carcinoma to promote tumorigenesis and metastasis. In situ hybridization confirmed that miR …
microRNAs and cancer: role in tumorigenesis, patient classification and therapy
E Hernando - Clinical and Translational Oncology, 2007 - Springer
MicroRNAs (miRNAs) are small non-coding RNAs that downregulate gene expression
during various crucial cell processes such as apoptosis, differentiation and development …
during various crucial cell processes such as apoptosis, differentiation and development …
A miR-200 microRNA cluster as prognostic marker in advanced ovarian cancer
X Hu, DM Macdonald, PC Huettner, Z Feng… - Gynecologic …, 2009 - Elsevier
OBJECTIVE: Ovarian cancer is one of the most deadly human cancers, resulting in over
15,000 deaths in the US each year. A reliable method that could predict disease outcome …
15,000 deaths in the US each year. A reliable method that could predict disease outcome …